Evidence map›Paper›PMID 27060868›Full record

SynthesisAlcoholism, clinical and experimental research2016

Alcohol-Induced Blackouts: A Review of Recent Clinical Research with Practical Implications and Recommendations for Future Studies.

Reagan R Wetherill, Kim Fromme

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.

  1. Pooled it
  2. Health goals, sex, and college enrollment: Impacts on young adult response to digital alcohol intervention.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
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  13. Daily-level associations between protective behavioral strategies, transdermal alcohol concentration, and alcohol-induced blackouts among young adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Reagan R WetherillDepartment of Psychiatry, Center for Studies of Addiction, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania.
Kim FrommeDepartment of Psychology, University of Texas at Austin, Austin, Texas.
The University of Texas at Austin · USUniversity of Pennsylvania · US

Funding

Genetic Mechanisms of Change in Trajectories of Drinking and Deviant BehaviorsR01AA020637 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI FROMME, KIM · 2012 to 2016
$2.3M
Effectiveness of Bavisant:Characterizing Individual DifferencesK23AA023894 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI WETHERILL, REAGAN R · 2015 to 2019
$856k
NIAAA NIH HHS K23 AA023894NIAAA NIH HHS R01 AA020637
6 · The paper itself

Abstract

backgroundAlcohol-induced blackouts, or memory loss for all or portions of events that occurred during a drinking episode, are reported by approximately 50% of drinkers and are associated with a wide range of negative consequences, including injury and death. As such, identifying the factors that contribute to and result from alcohol-induced blackouts is critical in developing effective prevention programs. Here, we provide an updated review (2010 to 2015) of clinical research focused on alcohol-induced blackouts, outline practical and clinical implications, and provide recommendations for future research.

methodsA comprehensive, systematic literature review was conducted to examine all articles published between January 2010 through August 2015 that focused on vulnerabilities, consequences, and possible mechanisms for alcohol-induced blackouts.

resultsTwenty-six studies reported on alcohol-induced blackouts. Fifteen studies examined prevalence and/or predictors of alcohol-induced blackouts. Six publications described the consequences of alcohol-induced blackouts, and 5 studies explored potential cognitive and neurobiological mechanisms underlying alcohol-induced blackouts.

conclusionsRecent research on alcohol-induced blackouts suggests that individual differences, not just alcohol consumption, increase the likelihood of experiencing an alcohol-induced blackout, and the consequences of alcohol-induced blackouts extend beyond the consequences related to the drinking episode to include psychiatric symptoms and neurobiological abnormalities. Prospective studies and a standardized assessment of alcohol-induced blackouts are needed to fully characterize factors associated with alcohol-induced blackouts and to improve prevention strategies.

Indexed as

Alcohol DrinkingAmnesiaHumansAlcoholBlackoutsEthanolMemory Impairments

Identifiers

PMID27060868
PMCPMC4844761
OpenAlexW2322808800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.