Evidence map›Paper›PMID 27060695›Full record

ArticleAdvanced healthcare materials2016

A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.

Young-Ah Lucy Lee, Shiyi Zhang, Jiaqi Lin, Robert Langer, Giovanni Traverso

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Mucosa-interfacing electronics.Nature reviews. Materials · 2022
    Review
  4. Article
  5. Defining optimal permeant characteristics for ultrasound-mediated gastrointestinal delivery.Journal of controlled release : official journal of the Controlled Release Society · 2017
    Article
  6. Intestinal mucoadhesive devices for oral delivery of insulin.Bioengineering & translational medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Young-Ah Lucy LeeDepartment of Chemical Engineering and Koch Institute for Integrative Cancer, Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Shiyi ZhangDepartment of Chemical Engineering and Koch Institute for Integrative Cancer, Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Jiaqi LinDepartment of Chemical Engineering and Koch Institute for Integrative Cancer, Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Robert LangerDepartment of Chemical Engineering and Koch Institute for Integrative Cancer, Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Giovanni TraversoDepartment of Chemical Engineering and Koch Institute for Integrative Cancer, Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Funding

CONTROLLED RELEASE OF MACROMOLECULESR01EB000244 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL, TRAVERSO, CARLO GIOVANNI · 2002 to 2021
$6.1M
Controlled Release of MacromoleculesR37EB000244 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL · 2008 to 2017
$3.9M
NIBIB NIH HHS R01 EB000244NIBIB NIH HHS R37 EB000244
6 · The paper itself

Abstract

A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side.

Indexed as

AdhesivesAnimalsDrug Delivery SystemsGastrointestinal TractHumansMucous MembraneSwineWaterAdhesivesWaterbioinspiredgastrointestinal retentionjanusmucoadhesiveomniphobic

Identifiers

PMID27060695
PMCPMC5283723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.