Evidence map›Paper›PMID 27060296›Full record

ReviewThe Journal of physiology2016

Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease.

Beth A Habecker, Mark E Anderson, Susan J Birren, Keiichi Fukuda, Neil Herring, Donald B Hoover, Hideaki Kanazawa, David J Paterson, Crystal M Ripplinger

Abstract readReview
In one paragraph

Review in The Journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. The Brain-Heart Network of Syncope.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Exploring the prospects, advancements, and challenges ofFrontiers in cellular neuroscience · 2024
    Article
  17. Article
  18. Human induced pluripotent stem cell-derived cardiac myocytes and sympathetic neurons in disease modelling.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beth A HabeckerDepartment of Physiology and Pharmacology, Department of Medicine Division of Cardiovascular Medicine and Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, 97239, USA.ORCID 0000-0002-4658-8730
Mark E AndersonJohns Hopkins Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
Susan J BirrenDepartment of Biology, Volen Center for Complex Systems, Brandeis University, Waltham, MA, 02453, USA.
Keiichi FukudaDepartment of Cardiology, Keio University School of Medicine, 35-Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Neil HerringBurdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.
Donald B HooverDepartment of Biomedical Sciences, Center of Excellence in Inflammation, Infectious Disease and Immunity, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA.
Hideaki KanazawaDepartment of Cardiology, Keio University School of Medicine, 35-Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
David J PatersonBurdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.
Crystal M RipplingerDepartment of Pharmacology, University of California, Davis, CA, 95616, USA.

Funding

Neurotrophins and post-infarct plasticity in cardiac sympathetic neuronsR01HL093056 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BETH A HABECKER · 2009 to 2026
$7.9M
The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
Mitochondrial Calmodulin Kinase II in Physiology and DiseaseR01HL070250 · NHLBI · VANDERBILT UNIVERSITY · PI ANDERSON, MARK E · 2002 to 2017
$5.2M
Thoracic Veins and Sustained Atrial FibrillationR01HL071140 · NHLBI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CHEN, PENG-SHENG · 2002 to 2014
$4.7M
Regulation of Sympathetic Function by InfarctionR01HL068231 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HABECKER, BETH A · 2001 to 2015
$4.3M
Methionine sulfoxide reductase A and oxidized CaMKII in structural heart diseaseR01HL079031 · NHLBI · UNIVERSITY OF IOWA · PI ANDERSON, MARK E · 2006 to 2015
$3.3M
CaMKII in Sinus Node Physiology and DiseaseR01HL096652 · NHLBI · UNIVERSITY OF IOWA · PI ANDERSON, MARK E · 2009 to 2016
$3.0M
Cholinergic anti-inflammatory mechanisms in sepsis and septic shockR15GM107949 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI HOOVER, DONALD B · 2014 to 2014
$337k
British Heart Foundation FS/15/8/31155NHLBI NIH HHS R01 HL068231NHLBI NIH HHS R01 HL070250NHLBI NIH HHS R01 HL071140NHLBI NIH HHS R01 HL079031NHLBI NIH HHS R01 HL093056NHLBI NIH HHS R01 HL096652NHLBI NIH HHS R01 HL111600NIGMS NIH HHS R15 GM107949
6 · The paper itself

Abstract

The nervous system and cardiovascular system develop in concert and are functionally interconnected in both health and disease. This white paper focuses on the cellular and molecular mechanisms that underlie neural-cardiac interactions during development, during normal physiological function in the mature system, and during pathological remodelling in cardiovascular disease. The content on each subject was contributed by experts, and we hope that this will provide a useful resource for newcomers to neurocardiology as well as aficionados.

Indexed as

AnimalsHeartHeart DiseasesHumansNeurotransmitter AgentsSynaptic TransmissionNeurotransmitter Agents

Identifiers

PMID27060296
PMCPMC4945713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.