Evidence map›Paper›PMID 27059708›Full record

ArticleClinical cardiology2016

Statin Use and Its Facility-Level Variation in Patients With Diabetes: Insight From the Veterans Affairs National Database.

Yashashwi Pokharel, Julia M Akeroyd, David J Ramsey, Ravi S Hira, Vijay Nambi, Tina Shah, LeChauncy D Woodard, David E Winchester, Christie M Ballantyne, Laura A Petersen and 1 more

Abstract readComparative Study
In one paragraph

Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Determinants of Statin Initiation Among Adult Diabetic Patients in Bonga, Ethiopia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Facility-Level Variations in Kidney Disease Care among Veterans with Diabetes and CKD.Clinical journal of the American Society of Nephrology : CJASN · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yashashwi PokharelSaint Luke's Mid-America Heart Institute, University of Missouri-Kansas City, Missouri.
Julia M AkeroydDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
David J RamseyDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
Ravi S HiraDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
Vijay NambiSection of Cardiovascular Research, Baylor College of Medicine, Houston, Texas.
Tina ShahDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
LeChauncy D WoodardDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
David E WinchesterMalcom Randall Veterans Affairs Medical Center, Gainesville, Florida.
Christie M BallantyneSection of Cardiovascular Research, Baylor College of Medicine, Houston, Texas.
Laura A PetersenDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
Salim S ViraniSection of Cardiovascular Research, Baylor College of Medicine, Houston, Texas.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMT32HL110837 · NHLBI · UNIVERSITY OF MISSOURI KANSAS CITY · PI JOHN A SPERTUS · 2012 to 2026
$5.0M
NCATS NIH HHS UL1 TR001427NHLBI NIH HHS T32 HL110837
6 · The paper itself

Abstract

We sought to determine use of any and at least moderate-intensity statin therapy in a national sample of patients with diabetes mellitus (DM), with the hypothesis that nationwide frequency and facility-level variation in statin therapy are suboptimal. We sampled patients with DM age 40 to 75 years receiving primary care between October 1, 2012, and September 30, 2013, at 130 parent facilities and associated community-based outpatient clinics in the Veterans Affairs Health Care System. We examined frequency and facility-level variation in use of any or at least moderate-intensity statin therapy (mean daily dose associated with ≥30% low-density lipoprotein cholesterol lowering). In 911 444 patients with DM, 68.3% and 58.4% were receiving any and moderate- to high-intensity statin therapy, respectively. Patients receiving statin had higher burden of cardiovascular disease, were more likely to be on nonstatin lipid-lowering therapy and to receive care at a teaching facility, and had more frequent primary-care visits. Median facility-level uses of any and at least moderate-intensity statin therapy were 68.7% (interquartile range, 65.9%-70.8%) and 58.6% (interquartile range, 55.8%-61.4%), respectively. After adjusting for several patient-related and some facility-related characteristics, the median rate ratios for any and moderate- to high-intensity statin therapy were 1.20 (95% confidence interval: 1.18-1.22) and 1.29 (95% confidence interval: 1.24-1.33) respectively, indicating 20% to 29% variation in statin use between 2 identical patients receiving care at 2 random facilities. Statin use was suboptimal in a national sample of patients with DM with modest facility-level variation, likely indicating differences in statin-prescribing patterns.

Indexed as

AdultAgedAmbulatory Care FacilitiesDatabases, FactualDiabetes MellitusDrug PrescriptionsDyslipidemiasFemaleGuideline AdherenceHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Hydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID27059708
PMCPMC4840034

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.