ArticleJournal of cardiothoracic surgery2016
Red blood cell distribution width predicts long term cardiovascular event after on-pump beating coronary artery bypass grafting.
Article in Journal of cardiothoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association of preoperative and postoperative systemic inflammatory markers with early mortality and morbidity after CABG surgery.Journal of cardiothoracic surgery · 2026Article
- Red Cell Distribution Width is Associated with Bleeding Complications after Coronary Artery Bypass Grafting.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Predictive Value of Preoperative Morphology Parameters in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery.Journal of cardiovascular development and disease · 2024Article
- Red blood cell distribution width predicts gastrointestinal bleeding after coronary artery bypass grafting.BMC cardiovascular disorders · 2022Observational
- Clinical Values and Underlying Mechanism Analysis of Serum miR-455-5p in Carotid Artery Stenosis.Journal of inflammation research · 2022Article
- Role of pre-operative red cell distribution width estimation in the prediction of in-hospital mortality after off-pump coronary artery bypass grafting.Journal of cardiothoracic surgery · 2021Article
- Red blood cell distribution width and outcomes following coronary artery bypass grafting: looking back and forth.Indian journal of thoracic and cardiovascular surgery · 2020Article
- Red cell distribution width associated with adverse cardiovascular outcomes in patients with chronic kidney disease.BMC nephrology · 2017Article
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Authors and funding
6 authors.
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Abstract
backgroundReports investigating the predictive value of red cell distribution width (RDW) on major cardiac and cardiovascular event (MACCE) following coronary artery bypass grafting (CABG) have major limitations, including lack of elimination of common factors affecting RDW levels, such as anemia. The purpose of this study is to identify the real effect of higher RDW level, free from the other factors, on MACCE following CABG.
methodsData of 500 consecutive, non-anemic patients (77.2 % male and mean age 63.05 ± 9.24) undergoing ONBHCAB between January 2007 and January 2010, were analyzed retrospectively.
resultsOverall MACCE was 7.8 % of all cases. Mean follow-up was 66.5 ± 9.96 months. In multivariate Cox regression analysis, RDW (P = 0.022) remained the only independent predictor of MACCE and the ROC analyze revealed an RDW cut-off value of 13.95 % predicting MACCE. Therefore, patients were grouped on this cut-off value. There were 238 patients in the lower RDW group (Group 1) and 262 patients in the higher RDW group (Group 2). Kaplan-Meier survival analysis of freedom from MACCE revealed significantly lower event free survival in Group 2 (P < 0.001 by the log-rank test). Group 2 showed a higher MACCE incidence in 1 year (P = 0.030), in 3 years (P < 0.001) and in 6 years (P < 0.001). The long-term follow-up was similar regarding noncardiovascular mortality.
conclusionAn RDW level greater than 13.95 % in hospital admission is independently associated with an increased incidence of MACCE after CABG. Physicians should be more aggressive in the management of these patients.
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