Evidence map›Paper›PMID 27059428›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2016

Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols.

Salim Javed, Mahipal Bodugam, Jessica Torres, Arghya Ganguly, Paul R Hanson

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Synthesis of Simplified 2-Desmethyl Sanctolide A Analogs.The Journal of organic chemistry · 2024
    Article
  2. Total Synthesis of Sanctolide A and Formal Synthesis of (2The Journal of organic chemistry · 2023
    Article
  3. Article
  4. Article
  5. P-Tether-Mediated, Iterative SOrganic letters · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Salim Javed *Department of Chemistry, University of Kansas, Lawrence, Kansas 66045 (USA).
Mahipal Bodugam *Department of Chemistry, University of Kansas, Lawrence, Kansas 66045 (USA).
Jessica TorresDepartment of Chemistry, University of Kansas, Lawrence, Kansas 66045 (USA).
Arghya GangulyDepartment of Chemistry, University of Kansas, Lawrence, Kansas 66045 (USA).
Paul R HansonDepartment of Chemistry, University of Kansas, Lawrence, Kansas 66045 (USA).

Funding

Methods for Bioactive Compound SynthesisR01GM077309 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HANSON, PAUL R. · 2007 to 2016
$2.4M
NIGMS NIH HHS R01 GM077309
6 · The paper itself

Abstract

A series of one-pot, sequential protocols was developed for the synthesis of novel macrocycles bearing α,β-unsaturated chemotypes. The method highlights a phosphate tether-mediated approach to establish asymmetry, and consecutive one-pot, sequential processes to access the macrocycles with minimal purification procedures. This library amenable strategy provided diverse macrocycles containing α,β-unsaturated carbon-, sulfur-, or phosphorus-based warheads.

Indexed as

Lactams, MacrocyclicMacrocyclic CompoundsNaphthalenesulfonatesStereoisomerismLactams, MacrocyclicMacrocyclic CompoundsNaphthalenesulfonatesnaphthosultoneheterocycleslactamsmacrocyclesone-pot reactionsphosphate-tether mediation

Identifiers

PMID27059428
PMCPMC5094705

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.