ArticleCell stem cell2016
Stem Cells Expand Insights into Human Brain Evolution.
Article in Cell stem cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Recent Expansions on Cellular Models to Uncover the Scientific Barriers Towards Drug Development for Alzheimer's Disease.Cellular and molecular neurobiology · 2019Review
- Modeling Neurological Diseases With Human Brain Organoids.Frontiers in synaptic neuroscience · 2018Review
- The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.Neuron · 2017Article
- Generating CNS organoids from human induced pluripotent stem cells for modeling neurological disorders.International journal of physiology, pathophysiology and pharmacology · 2017Review
- Lessons from Retinoblastoma: Implications for Cancer, Development, Evolution, and Regenerative Medicine.Trends in molecular medicine · 2016Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Substantial expansion in the number of cerebral cortex neurons is thought to underlie cognitive differences between humans and other primates, although the mechanisms underlying this expansion are unclear. Otani et al. (2016) utilize PSC-derived brain organoids to study how species-specific differences in cortical progenitor proliferation may underlie cortical evolution.
Indexed as
Identifiers
27058930What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.