SMITten by the Speed of Splicing.

Tracy L Johnson, Manuel Ares

Abstract readComment

In one paragraph

Article in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Unlocking Barley's Phosphorus Efficiency: The Emerging Role of RNA Processing in Low-Phosphorus Adaptation.Plants (Basel, Switzerland) · 2026
Review

4 · The record

Corrections and comments

Comment on
Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II.2016

5 · Who and what money

Authors and funding

2 authors.

Tracy L JohnsonMolecular, Cell, and Developmental Biology, Terasaki Life Sciences Building Room 5159, 610 Charles Young Drive East, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: tljohnson@ucla.edu.

Manuel AresDepartment of Molecular, Cell and Developmental Biology, Center for Molecular Biology of RNA, Sinsheimer Laboratories, 1156 High Street, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. Electronic address: ares@ucsc.edu.

Funding

STRUCTURE/FUNCTION OF YEAST SMALL NUCLEAR RNPSR01GM040478 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ARES, MANUEL · 1988 to 2021

$10.8M

6 · The paper itself

Abstract

Splicing occurs co-transcriptionally, but relative rates of splicing and transcription that might reveal mechanisms of their coordinated control have remained mysterious. Now, Carrillo Oesterreich et al. show that the fastest introns are gone nearly as soon as the 3' splice site is transcribed and that introns have distinct splicing kinetics with respect to polymerase progression along the gene.

Indexed as

IntronsRNA SplicingHumansRNA Splice SitesRNA Splice Sites

Identifiers

PMID27058658

DOI10.1016/j.cell.2016.03.035

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.