ArticleeLife2016
Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed, 263 citations in OpenAlex.
- The RLK7-MPK3/6-LEAFY PETIOLE signaling axis mediates growth inhibition during PIP peptide-induced immunity in Arabidopsis.Plant communications · 2026Article
- Plant peptide hormones: three decades of discovery and emerging paradigms.Plant physiology · 2026Review
- Cross-ribbon conformation defines peptide recognition in SCREW/CTNIP-NUT/HSL3 signalling.Nature plants · 2026Article
- A disulfide bond sculpts the CTNIP4 phytocytokine fold for recognition by the receptor kinase HSL3.Nature plants · 2026Article
- An LRR co-receptor kinase essential for systemic nitrogen-demand signalling.Nature plants · 2026Article
- Disulfide-bond-driven neck-ring-like conformation mediates SCREW recognition in plant immunity.Nature plants · 2026Article
- GhNAC47 activates GhSKS6-mediated cell wall remodeling to promote cotton chemical defoliation.The New phytologist · 2026Article
- The RhMPK3-RhLOB41-RhWRKY9 module orchestrates ethylene-induced petal abscission via dual control of ROS homeostasis in rose.Science advances · 2026Article
- Structure of the Arabidopsis receptor kinase SRF6 ectodomain determined from crystals obtained using the LRR crystallization screen.Acta crystallographica. Section D, Structural biology · 2026Article
- Structural basis for the activation of an LRR receptor by a single-disulfide-bridged peptide signal.Plant communications · 2026Article
- Plant Peptides on the Rise: From Historical Insight to Future Applications.Plant biotechnology journal · 2026Review
- Plant subtilases as key initiators of peptide ligand-receptor signaling.The Plant journal : for cell and molecular biology · 2026Review
- A hierarchical abscission program regulates reproductive allocation inHorticulture research · 2026Article
- Identification of the IDA peptide family in tomato and function of SlIDA8 in salt stress.BMC plant biology · 2026Article
- The HAESA family of receptor-like kinases: abscission pathways and emerging functions.Frontiers in plant science · 2026Review
- Article
- Abscission zones: cellular interfaces for the programmed separation of organs.Annals of botany · 2025Review
- Advances of Peptides for Plant Immunity.Plants (Basel, Switzerland) · 2025Review
- Identification of the Casparian strip integrity factor (CIF) gene family in Brassica napus and functional prediction of mature CIF small peptides.BMC plant biology · 2025Article
- Making a new epidermis after abscission.Nature plants · 2025Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants constantly renew during their life cycle and thus require to shed senescent and damaged organs. Floral abscission is controlled by the leucine-rich repeat receptor kinase (LRR-RK) HAESA and the peptide hormone IDA. It is unknown how expression of IDA in the abscission zone leads to HAESA activation. Here we show that IDA is sensed directly by the HAESA ectodomain. Crystal structures of HAESA in complex with IDA reveal a hormone binding pocket that accommodates an active dodecamer peptide. A central hydroxyproline residue anchors IDA to the receptor. The HAESA co-receptor SERK1, a positive regulator of the floral abscission pathway, allows for high-affinity sensing of the peptide hormone by binding to an Arg-His-Asn motif in IDA. This sequence pattern is conserved among diverse plant peptides, suggesting that plant peptide hormone receptors may share a common ligand binding mode and activation mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.