Evidence map›Paper›PMID 27058123›Full record

ArticleNeurotoxicology2017

Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.

Jason P Magby, Jason R Richardson

Open access · greenAbstract read
In one paragraph

Article in Neurotoxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  8. Review
  9. Genetic and Environmental Factors in Parkinson's Disease Converge on Immune Function and Inflammation.Movement disorders : official journal of the Movement Disorder Society · 2021
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jason P MagbyEnvironmental and Occupational Health Sciences Institute and Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA.
Jason R RichardsonEnvironmental and Occupational Health Sciences Institute and Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA; Northeast Ohio Medical University Department of Pharmaceutical Sciences, Rootstown, OH 44272, USA. Electronic address: jrichardson@neomed.edu.
Environmental and Occupational Health Sciences Institute · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
Mechanisms of Pesticide-Induced Neurobehavioral Deficits: Relevance to ADHDR01ES015991 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI RICHARDSON, JASON R · 2007 to 2011
$3.2M
Developmental Pyrethroid Exposure and ADHDR21ES013828 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI RICHARDSON, JASON R · 2005 to 2007
$455k
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS R01 ES015991NIEHS NIH HHS R21 ES013828
6 · The paper itself

Abstract

Pyrethroid insecticide use has increased over recent years because of their low to moderate acute toxicity in mammals. However, there is increasing concern over the potential detrimental effects of pyrethroids on developing animals. Most recently, we have shown that developmental exposure to deltamethrin results in long-term neurobehavioral effects. Pyrethroids exert their toxicity by acting on the voltage-gated sodium channel (Na

Indexed as

AnimalsBrain-Derived Neurotrophic FactorCerebral CortexCorpus StriatumFemaleInsecticidesMaleMice, Inbred C57BLNeuronsNitrilesPregnancyPrenatal Exposure Delayed EffectsPyrethrinsRNA, MessengerVoltage-Gated Sodium ChannelsBrain-Derived Neurotrophic FactordecamethrinInsecticidesNitrilesPyrethrinsRNA, MessengerVoltage-Gated Sodium ChannelsBDNFDeltamethrinNeurodevelopmentalPyrethroidSodium channel

Identifiers

PMID27058123
PMCPMC8669832
OpenAlexW2313960564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.