SynthesisThe Journal of cardiovascular nursing
The Effectiveness of Medication Adherence Interventions Among Patients With Coronary Artery Disease: A Meta-analysis.
Synthesis in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Interventions to Improve Medication Adherence in Hypertensive Patients: Systematic Review and Meta-analysis.Current hypertension reports · 2015Pooled it
- Understanding the Effect of a Healthcare Provider-Led Family Planning Support Intervention on Contraception use and Pregnancy Desires among Postpartum Women Living with HIV in Southwestern Uganda.AIDS and behavior · 2022Trial
- Effects of a pharmaceutical care intervention on clinical outcomes and patient adherence in coronary heart disease: the MIMeRiC randomized controlled trial.BMC cardiovascular disorders · 2021Trial
- Analysis of nursing consultations for people with systemic arterial hypertension in Primary Health Care.Revista latino-americana de enfermagem · 2026Article
- Therapeutic Adherence in Cardiovascular Diseases: Insights from the Patient and Physician-A Narrative Review.Advances in therapy · 2026Review
- Effectiveness of Pharmacist-Led Intervention on Medication Adherence in Chronic Diseases: A Systematic Review of Randomized Controlled Trials.Patient preference and adherence · 2025Review
- Income and antiplatelet adherence following percutaneous coronary intervention.International journal of cardiology. Cardiovascular risk and prevention · 2022Article
- The Effect of Applying the Information-Motivation-Behavioral Skills Model on Treatment Adherence in Patients with Cardiovascular Disease: A Quasi-Experimental Study.International journal of community based nursing and midwifery · 2021Article
- Healthcare Provider Perspectives on Adherence to Adjuvant Endocrine Therapy after Breast Cancer.Current oncology (Toronto, Ont.) · 2021Article
- Influence of Diversity Nursing on Patients' Rehabilitation in Cardiology Treatment.Journal of healthcare engineering · 2021Article
- Health behaviour change in cardiovascular disease prevention and management: meta-review of behaviour change techniques to affect self-regulation.Health psychology review · 2020Article
- Self-regulation mechanisms in health behavior change: a systematic meta-review of meta-analyses, 2006-2017.Health psychology review · 2020Article
- Effectiveness of interventions targeting self-regulation to improve adherence to chronic disease medications: a meta-review of meta-analyses.Health psychology review · 2020Article
- Examining overlap of included studies in meta-reviews: Guidance for using the corrected covered area index.Research synthesis methods · 2020Article
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea: Recommendations for Cardiac Rehabilitation and Secondary Prevention after Acute Coronary Syndrome.Korean circulation journal · 2019Review
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea.The Korean journal of thoracic and cardiovascular surgery · 2019Article
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea.Annals of rehabilitation medicine · 2019Article
- Review
- Measuring the Value of Epilepsy Nurses.Epilepsy currentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDespite the known benefits of medication therapy for secondary prevention of coronary artery disease (CAD), many patients do not adhere to prescribed medication regimens. Medication nonadherence is associated with poor health outcomes and higher healthcare cost.
objectiveThe purpose of this meta-analysis was to determine the overall effectiveness of interventions designed to improve medication adherence (MA) among adults with CAD. In addition, sample, study design, and intervention characteristics were explored as potential moderators to intervention effectiveness.
methodsComprehensive search strategies helped in facilitating the identification of 2-group, treatment-versus-control-design studies testing MA interventions among patients with CAD. Data were independently extracted by 2 trained research specialists. Standardized mean difference effect sizes were calculated for eligible primary studies, adjusted for bias, and then synthesized under a random-effects model. Homogeneity of variance was explored using a conventional heterogeneity statistic. Exploratory moderator analyses were conducted using meta-analytic analogs for analysis of variance and regression for dichotomous and continuous moderators, respectively.
resultsTwenty-four primary studies were included in this meta-analysis. The overall effect size of MA interventions, calculated from 18,839 participants, was 0.229 (P < .001). The most effective interventions used nurses as interventionists, initiated interventions in the inpatient setting, and informed providers of patients' MA behaviors. Medication adherence interventions tested among older patients were more effective than those among younger patients. The interventions were equally effective regardless of number of intervention sessions, targeting MA behavior alone or with other behaviors, and the use of written instructions only.
conclusionsInterventions to increase MA among patients with CAD were modestly effective. Nurses can be instrumental in improving MA among these patients. Future research is needed to investigate nurse-delivered MA interventions across varied clinical settings. In addition, more research testing MA interventions among younger populations and more racially diverse groups is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.