Evidence map›Paper›PMID 27057473›Full record

ArticleOncoimmunology2016

Phenotypic and functional characteristics of CD39

F Figueiró, L Muller, S Funk, E K Jackson, A M O Battastini, T L Whiteside

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 127 citations in OpenAlex.

  1. Review
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  10. Article
  11. Article
  12. Review
  13. Adenosine-generating CD39Life science alliance · 2025
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

F FigueiróPrograma de Pós-Graduação em Ciências Biológicas, Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul , Porto Alegre, RS, Brazil.
L MullerDepartment of Pathology, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute , Pittsburgh, PA, USA.
S FunkDepartment of Pathology, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute , Pittsburgh, PA, USA.
E K JacksonDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.
A M O BattastiniPrograma de Pós-Graduação em Ciências Biológicas, Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
T L WhitesideDepartment of Pathology, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute , Pittsburgh, PA, USA.
UPMC Hillman Cancer Center · USUniversidade Federal do Rio Grande do Sul · BRUniversity of Pittsburgh · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
2,3 cAMP in Traumatic Brain InjuryR01NS087978 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY, KOCHANEK, PATRICK M · 2014 to 2018
$1.7M
Restoring anti-tumor immunity in the microenvironment of head and neck cancerR01CA168628 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHITESIDE, THERESA L. · 2013 to 2017
$1.7M
NCI NIH HHS R01 CA168628NIDDK NIH HHS P30 DK079307NINDS NIH HHS R01 NS087978
6 · The paper itself

Abstract

CD39 and CD73 are key enzymes in the adenosine (ADO) pathway. ADO modulates pathophysiological responses of immune cells, including B cells. It has recently emerged that a subpopulation of ADO-producing CD39

Indexed as

5′-AMP and adenosine productionAutocrine regulationCD39 and CD73 expressionregulatory B cells (Breg)T-cell suppression

Identifiers

PMID27057473
PMCPMC4801473
OpenAlexW2345447295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.