Evidence map›Paper›PMID 27057426›Full record

ArticleOncoimmunology2016

Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients.

Audrey Hennequin, Valentin Derangère, Romain Boidot, Lionel Apetoh, Julie Vincent, David Orry, Jean Fraisse, Sylvain Causeret, François Martin, Laurent Arnould and 3 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 4 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed, 4 syntheses or guidelines pooled it, 222 citations in OpenAlex.

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  10. FOXP3Medical sciences (Basel, Switzerland) · 2026
    Article
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  20. Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article

91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Audrey HennequinDepartment of Medical Oncology Center Georges François Leclerc; Dijon, France; Faculté des Sciences de Santé; Université de Bourgogne; Dijon, France.
Valentin DerangèreFaculté des Sciences de Santé; Université de Bourgogne; Dijon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France; Department of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc; Dijon, France.
Romain BoidotInstitut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France; Department of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc; Dijon, France.
Lionel ApetohDepartment of Medical Oncology Center Georges François Leclerc; Dijon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France; Department of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc; Dijon, France.
Julie VincentDepartment of Medical Oncology Center Georges François Leclerc ; Dijon, France.
David OrryDepartment of Surgical Oncology. Center Georges François Leclerc ; Dijon, France.
Jean FraisseDepartment of Surgical Oncology. Center Georges François Leclerc ; Dijon, France.
Sylvain CauseretDepartment of Surgical Oncology. Center Georges François Leclerc ; Dijon, France.
François MartinFaculté des Sciences de Santé; Université de Bourgogne; Dijon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France.
Laurent ArnouldDepartment of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc ; Dijon, France.
Françoise BeltjensDepartment of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc ; Dijon, France.
François GhiringhelliDepartment of Medical Oncology Center Georges François Leclerc; Dijon, France; Faculté des Sciences de Santé; Université de Bourgogne; Dijon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France; Department of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc; Dijon, France.
Sylvain LadoireDepartment of Medical Oncology Center Georges François Leclerc; Dijon, France; Faculté des Sciences de Santé; Université de Bourgogne; Dijon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 866; Dijon, France; Department of Biology and Pathology of Tumors. Plateform of Genetic; Immunology and Histology of Solid Tumors; Centre Georges-François Leclerc; Dijon, France; Faculté des Sciences de Santé; Université de Bourgogne; Dijon, France.
Centre Georges François Leclerc · FRUniversité des Sciences de la Santé · GASolid (South Korea) · KRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-infiltrating T and B lymphocytes could have the potential to affect cancer prognosis. The objective of this study was to investigate the prognostic significance of tumor infiltration by CD8 and CD4 T cells, and B lymphocytes in patients with localized gastric cancer. In a retrospective cohort of 82 patients with localized gastric cancer and treated by surgery we quantitatively assessed by immunohistochemistry on surgical specimen, immune infiltrates of IL-17

Indexed as

B cellsgastric cancerhistologyhuman tumorsprognosisT-bet

Identifiers

PMID27057426
PMCPMC4801425
OpenAlexW2303799488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.