ArticleMaternal health, neonatology and perinatology2015
Severe asymptomatic maternal antepartum hyponatremia leading to neonatal seizures: prevention is better than cure.
Article in Maternal health, neonatology and perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Electrolyte homeostasis in pregnancy: from physiological adaptations to clinical disturbances - a nephrologist's perspective.Frontiers in nephrology · 2026Review
- Case report: Acute severe hyponatremia-induced seizures in a newborn: a community-acquired case and literature review.Frontiers in pharmacology · 2024Article
- Severe hyponatraemia peripartum associated with omeprazole therapy.Obstetric medicine · 2023Article
- Overconsumption of fluids during labour leading to water intoxication and a tonic-clonic seizure in a healthy labourer.BMJ case reports · 2021Article
- Hyponatraemia reversibly affects human myometrial contractility. An in vitro pilot study.PloS one · 2020Article
- The peripartum management of diabetes.BJA education · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-delivery maternal electrolyte derangements may reflect themselves in the newborn, since placental homeostasis determines electrolyte equilibrium between mother and fetus. CASE PRESENTATION: A term newborn, transferred to our Neonatal Intensive Care Unit 1 h after birth for an apnoea episode, presented with initially left-sided, and subsequently generalized tonic-clonic seizures due to severe hyponatremia (119 mmol/L). Seizures rapidly ceased after electrolyte correction plus a phenobarbital bolus. Deep hyponatremia was also detected in the mother (123 mmol/L).
conclusionsAs placental homeostasis determines electrolytes equilibrium between mother and fetus, obstetrics and neonatologists should be aware that any maternal dyselectrolytemia will reflect itself in the newborn; hence, it is fundamental to detect possible maternal electrolyte imbalances before delivery, in order to be prepared to timely correction of electrolyte derangements in the newborn.
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