Evidence map›Paper›PMID 27057338›Full record

ReviewMaternal health, neonatology and perinatology2015

A physiologic approach to cord clamping: Clinical issues.

Susan Niermeyer

Registry-linked trialAbstract readReview
In one paragraph

Review in Maternal health, neonatology and perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03200301 (Effect of Intact Umbilical Cord Milking Versus Immediate Cord Clamping on Neonatal Outcomes and First Year Neurodevelopmental Outcomes in Very Preterm Infants - A Randomised Controlled Trial), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03200301 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effect of Intact Umbilical Cord Milking Versus Immediate Cord Clamping on Neonatal Outcomes and First Year Neurodevelopmental Outcomes in Very Preterm Infants - A Randomised Controlled Trial

TypeinterventionalSponsorJubilee Mission Medical College and Research InstituteRan2018 to 2024Enrolled250ConditionsPreterm Infant, Umbilical Cord MilkingArmsIntact Umbilical Cord Milking
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Factors associated with umbilical cord clamping in term newborns.Revista da Escola de Enfermagem da U S P · 2022
    Article
  7. Delivery room care and neonatal resuscitation while on intact placental circulation: an open-label, single-arm study.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  8. Article
  9. Article
  10. Delayed cord clamping in preterm infants: is it time to become standard practice?Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  11. Clinical aspects of incorporating cord clamping into stabilisation of preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2018
    Review
  12. Golden hour of neonatal life: Need of the hour.Maternal health, neonatology and perinatology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Susan NiermeyerSection of Neonatology, University of Colorado School of Medicine, 13121 E. 17th Avenue, Mail Stop 8402, Aurora, CO 80045 USA.ORCID 0000-0001-6310-8519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent experimental physiology data and a large, population-based observational study have changed umbilical cord clamping from a strictly time-based construct to a more complex equilibrium involving circulatory changes and the onset of respirations in the newly born infant. However, available evidence is not yet sufficient to optimize the management of umbilical cord clamping.

findingsCurrent guidelines vary in their recommendations and lack advice for clinicians who face practical dilemmas in the delivery room. This review examines the evidence around physiological outcomes of delayed cord clamping and cord milking vs. immediate cord clamping. Gaps in the existing evidence are highlighted, including the optimal time to clamp the cord and the interventions that should be performed before clamping in infants who fail to establish spontaneous respirations or are severely asphyxiated, as well as those who breathe spontaneously.

conclusionBehavioral and technological changes informed by further research are needed to promote adoption and safe practice of physiologic cord clamping.

Indexed as

Infant, NewbornInfant, PrematureUmbilical cord, Placental transfusion, Resuscitation, Respiration

Identifiers

PMID27057338
PMCPMC4823683

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.