ArticleMaternal health, neonatology and perinatology2015
Measuring cardiac changes using electrical impedance during delayed cord clamping: a feasibility trial.
Article in Maternal health, neonatology and perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Cardiac Output During Delayed Umbilical Cord Clamping
Hemodynamic Effects of Delayed Umbilical Cord Clamping in Full-term Newborns
Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Mode of Delivery and Neonatal Transition: Insights from Electrical Cardiometry.Children (Basel, Switzerland) · 2025Article
- Fetal to neonatal transition: what additional information can be provided by cerebral near infrared spectroscopy?Pediatric research · 2024Review
- Impact of cord clamping on haemodynamic transition in term newborn infants.Archives of disease in childhood. Fetal and neonatal edition · 2024Article
- Hemodynamic parameters after Delayed Cord Clamping (DCC) in term neonates: a prospective observational study.BMC pediatrics · 2022Observational
- In-Silico Evaluation of Anthropomorphic Measurement Variations on Electrical Cardiometry in Neonates.Children (Basel, Switzerland) · 2021Article
- Cardiac Output and Cerebral Oxygenation in Term Neonates during Neonatal Transition.Children (Basel, Switzerland) · 2021Article
- Non-invasive Cardiac Output Monitoring in Neonates.Frontiers in pediatrics · 2020Review
- Effect of early versus delayed cord clamping in neonate on heart rate, breathing and oxygen saturation during first 10 minutes of birth - randomized clinical trial.Maternal health, neonatology and perinatology · 2019Article
- Cardiac Output Monitoring in Preterm Infants.Frontiers in pediatrics · 2018Review
- Providing a Placental Transfusion in Newborns Who Need Resuscitation.Frontiers in pediatrics · 2017Review
- Commentary: Enhanced Monitoring of the Preterm Infant during Stabilization in the Delivery Room.Frontiers in pediatrics · 2016Article
- Motherside care of the term neonate at birth.Maternal health, neonatology and perinatology · 2016Review
- The timing of umbilical cord clamping at birth: physiological considerations.Maternal health, neonatology and perinatology · 2016Review
- Enhanced Monitoring of the Preterm Infant during Stabilization in the Delivery Room.Frontiers in pediatrics · 2016Review
- Response: Commentary: Enhanced Monitoring of the Preterm Infant during Stabilization in the Delivery Room.Frontiers in pediatrics · 2016Article
- A physiologic approach to cord clamping: Clinical issues.Maternal health, neonatology and perinatology · 2015Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo date no study has attempted to continuously evaluate changes in hemodynamics during delayed cord clamping in humans. We aimed to demonstrate 1. the feasibility of measurements of hemodynamics during delayed cord clamping and 2. to describe the changes that occur over each minute.
resultsAfter vaginal delivery, term infants (37(0)-41(6) weeks) were placed on a Life Start® bed 10-20 cm below the placenta. Transcutaneous sensors were placed on the neck and chest to determine heart rate, stroke volume and cardiac output at each beat. Once a signal was obtained, first 5 values (taken every beat) were averaged and the percent change for each subject from baseline was calculated. 20 infants were enrolled and all had a reliable signal obtained from transcutaneous sensors and had a delay in cord clamping for about 5 minutes. Cardiac output increased from 2 to 5 minutes of life (p = 0.008). For every minute of life the cord was kept unclamped, the stroke volume increased 13.1% ± 12.3 (p = 0.0001) and cardiac output increased 12.6% ± 6.3 from baseline (p < 0.0001). While the majority of infants continued to have an increase in cardiac output at 5 minutes of life, 7/20 infants reached their peak cardiac output at 188 ± 41 seconds of life.
conclusionsThis study demonstrates that hemodynamic measures could be successfully obtained during the first five minutes of birth and while a newborn was receiving delayed cord clamping. This study also provides reference values for changes in cardiac output and stroke volume in well term infants during delayed cord clamping.
trial registrationClinical Trials.gov NCT02195037 Registered 17 July 2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.