Evidence map›Paper›PMID 27057292›Full record

ReviewMethodist DeBakey cardiovascular journal

Atrial Fibrillation and Hypertension: Mechanistic, Epidemiologic, and Treatment Parallels.

Adedotun A Ogunsua, Amir Y Shaikh, Mohamed Ahmed, David D McManus

Open access · diamondAbstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Atrial Myopathy Underlying Atrial Fibrillation.Arrhythmia & electrophysiology review · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adedotun A OgunsuaUniversity of Massachusetts Medical School, Worcester, Massachusetts.
Amir Y ShaikhUniversity of Massachusetts Medical School, Worcester, Massachusetts.
Mohamed AhmedUniversity of Massachusetts Medical School, Worcester, Massachusetts.
David D McManusUniversity of Massachusetts Medical School, Worcester, Massachusetts.
University of Massachusetts Chan Medical School · US

Funding

TRACE-COREU01HL105268 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2010 to 2013
$5.8M
University of Massachusetts Center for Clinical and Translational ScienceKL2RR031981 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SULLIVAN, JOHN LEWIS · 2010 to 2011
$1.2M
Arrhythmia Detection Using a Smart PhoneR15HL121761 · NHLBI · WORCESTER POLYTECHNIC INSTITUTE · PI CHONG, JO WOON · 2014 to 2014
$389k
NCRR NIH HHS KL2 RR031981NCRR NIH HHS KL2RR031981NHLBI NIH HHS 1R15HL121761NHLBI NIH HHS R15 HL121761NHLBI NIH HHS U01 HL105268NHLBI NIH HHS U01HL105268
6 · The paper itself

Abstract

Atrial fibrillation (AF) is an increasingly prevalent condition and the most common sustained arrhythmia encountered in ambulatory and hospital practice. Several clinical risk factors for AF include age, sex, valvular heart disease, obesity, sleep apnea, heart failure, and hypertension (HTN). Of all the risk factors, HTN is the most commonly encountered condition in patients with incident AF. Hypertension is associated with a 1.8-fold increase in the risk of developing new-onset AF and a 1.5-fold increase in the risk of progression to permanent AF. Hypertension predisposes to cardiac structural changes that influence the development of AF such as atrial remodeling. The renin angiotensin aldosterone system has been demonstrated to be a common mechanistic link in the pathogenesis of HTN and AF. Importantly, HTN is one of the few modifiable AF risk factors, and guideline-directed management of HTN may reduce the incidence of AF.

Indexed as

Atrial FibrillationComorbidityHumansHypertensionIncidencePrevalencePrognosisRisk AssessmentRisk FactorsACE inhibitorsarrhythmiasbenign essential hypertensionnonvalvular atrial fibrillationRAAS pathway

Identifiers

PMID27057292
PMCPMC4814009
OpenAlexW2287802819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.