Evidence map›Paper›PMID 27057265›Full record

ArticleCurrent bladder dysfunction reports2016

The Burden of Overactive Bladder on US Public Health.

W Stuart Reynolds, Jay Fowke, Roger Dmochowski

4 registry-linked trialsAbstract read
In one paragraph

Article in Current bladder dysfunction reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05099419 early_phase1unknown statusnot on this mapstarted 2021, after this paper: background citation

Motor Cortical Neuromodulation With Repetitive Transcranial Magnetic Stimulation in Women With Overactive Bladder and Urgency Urinary Incontinence

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2022Enrolled10ConditionsOveractive Bladder, Urge IncontinenceArmsRepetitive Transcranial Magnetic Stimulation
NCT05221021 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Vaginal Estradiol vs Oral Beta-3 Agonist for Treatment of Overactive Bladder Syndrome: A Single-Therapy, Double-Blind, Randomized Controlled Trial

TypeinterventionalSponsorWalter Reed National Military Medical CenterRan2022 to 2027Enrolled152ConditionsOveractive Bladder SyndromeArmsVaginal estrogen, Mirabegron 50 MG [Myrbetriq]
NCT06387329 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Urinary Tract Infection Prophylaxis In Intradetrusor OnabotulinumtoxinA Procedures: A Randomized Controlled Trial

TypeinterventionalSponsorWalter Reed National Military Medical CenterRan2024 to 2025Enrolled100ConditionsOveractive Bladder, Bladder Pain SyndromeArmsNitrofurantoin 100 MG
NCT07171424 nacompletednot on this mapstarted 2026, after this paper: background citation

Moving Beyond p-Values: Minimal Clinically Important Difference for Overactive Bladder Questionnaire - Version 8 and International Consultation on Incontinence Questionnaire - Short Form in Patients With Overactive Bladder Syndrome

TypeinterventionalSponsorArtvin Coruh UniversityRan2026 to 2026Enrolled104ConditionsOveractive Bladder SyndromeArmsBehavioral therapy and transcutaneous posterior tibial nerve stimulation
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. The status of health-related quality of life among older adults with overactive bladder: a cross-sectional analysis of the Yamagata Cohort Study in Japan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

W Stuart ReynoldsDepartment of Urologic Surgery, Female Pelvic Medicine and Reconstructive Surgery, Vanderbilt University Medical Center, A1302 Medical Center North, Nashville, TN 37232, USA.
Jay FowkeDepartment of Urologic Surgery, Vanderbilt Epidemiology Center, Institute of Medicine and Public Health, Vanderbilt University Medical Center, 12th floor, Nashville, TN 37232, USA.
Roger DmochowskiDepartment of Urologic Surgery, Female Pelvic Medicine and Reconstructive Surgery, Vanderbilt University Medical Center, A1302 Medical Center North, Nashville, TN 37232, USA.

Funding

Afferent Hyperactivity Mechanisms in Overactive Bladder SyndromeK23DK103910 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI REYNOLDS, WILLIAM STUART · 2015 to 2019
$737k
NIDDK NIH HHS K23 DK103910
6 · The paper itself

Abstract

Overactive bladder (OAB) is a highly prevalent symptom condition that affects millions of US men and women. Not only can the symptoms of OAB be very bothersome, but OAB can have significant detrimental effects on many aspects of individuals' lives, representing a particularly impactful health burden to quality of life and productivity. Estimates of the individual and societal costs for the management of OAB continue to rise, particularly as effective treatments remain elusive. As such, OAB represents a significant public health burden to the USA.

Indexed as

EpidemiologyHealth economicsOveractive bladderPublic health

Identifiers

PMID27057265
PMCPMC4821440

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.