Evidence map›Paper›PMID 27057203›Full record

ReviewImmunity & ageing : I & A2016

Nutrition, aging and cancer: lessons from dietary intervention studies.

Giuseppe Carruba, Letizia Cocciadiferro, Antonietta Di Cristina, Orazia M Granata, Cecilia Dolcemascolo, Ildegarda Campisi, Maurizio Zarcone, Maria Cinquegrani, Adele Traina

Registry-linked trialAbstract readReview
In one paragraph

Review in Immunity & ageing : I & A, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05615883 (Effects of Acute and Chronic Exercise on Myeloid-Derived Suppressor Cells in Melanoma Patients), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05615883 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Acute and Chronic Exercise on Myeloid-Derived Suppressor Cells in Melanoma Patients

TypeinterventionalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2020 to 2023Enrolled16ConditionsMelanomaArmsAEP Group Walking Sessions, CEP Group Walking Sessions
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Ageing: from inflammation to cancer.Immunity & ageing : I & A · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuseppe CarrubaDivision of Research and Internationalization, ARNAS-Civico Di Cristina e Benfratelli, Palermo, Italy.
Letizia CocciadiferroResearch Laboratories Dr. Nicola Locorotondo, Palermo, Italy.
Antonietta Di CristinaResearch Laboratories Dr. Nicola Locorotondo, Palermo, Italy.
Orazia M GranataClinical Pathology, "G. DI Cristina" Pediatric Hospital ARNAS-Civico Di Cristina e Benfratelli, Palermo, Italy.
Cecilia DolcemascoloDivision of Research and Internationalization, ARNAS-Civico Di Cristina e Benfratelli, Palermo, Italy.
Ildegarda CampisiDivision of Research and Internationalization, ARNAS-Civico Di Cristina e Benfratelli, Palermo, Italy.
Maurizio ZarconeDivision of Research and Internationalization, ARNAS-Civico Di Cristina e Benfratelli, Palermo, Italy.
Maria CinquegraniResearch Laboratories Dr. Nicola Locorotondo, Palermo, Italy.
Adele TrainaThe Diana Project, National Cancer Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is convincing epidemiological and clinical evidence that, independent of aging, lifestyle and, notably, nutrition are associated with development or progression of major human cancers, including breast, prostate, colorectal tumors, and an increasingly large collection of diet-related cancers. Mechanisms underlying this association are mostly related to the distinct epigenetic effects of different dietary patterns. In this context, Mediterranean diet has been reported to significantly reduce mortality rates for various chronic illnesses, including cardiovascular diseases, neurodegenerative diseases and cancer. Although many observational studies have supported this evidence, dietary intervention studies using a Mediterranean dietary pattern or its selected food components are still limited and affected by a rather large variability in characteristics of study subjects, type and length of intervention, selected end-points and statistical analysis. Here we review data of two of our intervention studies, the MeDiet study and the DiMeSa project, aimed at assessing the effects of traditional Mediterranean diet and/or its component(s) on a large panel of both plasma and urine biomarkers. Both published and unpublished results are presented and discussed.

Identifiers

PMID27057203
PMCPMC4823849

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.