Evidence map›Paper›PMID 27056880›Full record

Observational studyCirculation. Heart failure2016

Relation of Magnesium Intake With Cardiac Function and Heart Failure Hospitalizations in Black Adults: The Jackson Heart Study.

Tracey H Taveira, Danielle Ouellette, Alev Gulum, Gaurav Choudhary, Charles B Eaton, Simin Liu, Wen-Chih Wu

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Circulation. Heart failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Tracey H TaveiraFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Danielle OuelletteFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Alev GulumFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Gaurav ChoudharyFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Charles B EatonFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Simin LiuFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles.
Wen-Chih WuFrom the Department of Medicine, Veterans Affairs Medical Center, Center of Innovation for Long Term Services and Support, Providence, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Pharmacy Practice, University of Rhode Island, College of Pharmacy, Kingston, RI (T.H.T., D.O., A.G., G.C., W.-C.W.); Department of Medicine, Warren Alpert School of Medicine of Brown University, Providence, RI (T.H.T., G.C., W.-C.W.); Center for Primary Care and Prevention (C.B.E.) and the Department of Family Medicine (C.B.E.), Memorial Hospital of Rhode Island, Pawtucket, RI; Department of Epidemiology, Brown University School of Public Health, Providence, RI (C.B.E., S.L., W.-C.W.); and The Program on Genomics and Nutrition, Center for Metabolic Disease Prevention, Departments of Epidemiology (S.L.), Medicine (S.L.), and Obstetrics and Gynecology (S.L.), University of California, Los Angeles. Wen-chih.wu@va.gov.
University of Rhode Island · USBrown University · USMemorial Hospital of Rhode Island · USRhode Island College · US

Funding

NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CPHS HHS HHSN268201300046CPHS HHS HHSN268201300047CPHS HHS HHSN268201300048CPHS HHS HHSN268201300049CPHS HHS HHSN268201300050C
6 · The paper itself

Abstract

backgroundLittle is known about magnesium intake and risk of heart failure (HF) hospitalizations, particularly in blacks. We hypothesize that magnesium intake relates to HF hospitalization in blacks. METHODS AND

resultsFrom the Jackson Heart Study cohort (n=5301), we studied 4916 blacks recruited during 2000 to 2004 in Jackson (Mississippi), who completed an 158-item Food-Frequency Questionnaire that included dietary supplements. Daily magnesium intake derived from the questionnaire was divided by the body weight to account for body storage and stratified by quartiles (0.522-2.308, 2.309-3.147, 3.148-4.226, and ≥4.227 mg magnesium intake/kg). Cox proportional hazards modeling assessed the association between quartiles of magnesium intake/kg and hospitalizations for HF adjusting for HF risk, energy intake, and dietary factors. The cohort had a mean age=55.3 (SD=12.7 years) and composed of 63.4% women, 21.6% diabetes mellitus, 62.7% hypertension, 7.1% coronary disease, and 2.8% with known HF. When compared with participants in the first quartile of magnesium intake/kg, those with higher magnesium intake (>2.308 mg/kg) had decreased risk of HF admission, with adjusted hazard ratios of 0. 66(95% confidence interval, 0.47-0.94) in the second quartile to 0.47 (95% confidence interval, 0.27-0.82) in the highest quartile. Results were similar when individuals with previously diagnosed HF (2.8%) were excluded or when the analysis was repeated using quartiles of magnesium intake without accounting for body weight.

conclusionsMagnesium intake <2.3 mg/kg was related to increased risk of subsequent HF hospitalizations. Future studies are needed to test whether serum magnesium levels predict risk of HF.

Indexed as

Black or African AmericanDietDietary SupplementsHospitalizationAdultAgedAged, 80 and overAge FactorsComorbidityDiastoleEchocardiography, DopplerFemaleHeart FailureHumansKaplan-Meier EstimateLinear ModelsMagnesiumAfrican Continental Ancestry Groupbiomarkersheart failure

Identifiers

PMID27056880
PMCPMC4826717
OpenAlexW2548546253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.