Evidence map›Paper›PMID 27056590›Full record

ArticleBMJ open2016

Weekend versus weekday transplant surgery and outcomes after kidney transplantation in the USA: a retrospective national database analysis.

Seema Baid-Agrawal, Peter Martus, Harold Feldman, Holly Kramer

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Seema Baid-AgrawalDepartment of Nephrology and Transplant Center, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-8192-1079
Peter MartusInstitute for Clinical Epidemiology and Applied Biometry, University Clinic of Tuebingen, Tuebingen, Germany.
Harold FeldmanCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.
Holly KramerDepartment of Public Health Sciences and Medicine, Division of Nephrology and Hypertension, Loyola Medical Center, Maywood, Illinois, USA.
Loyola University Medical Center · USSahlgrenska University Hospital · SEUniversity of Pennsylvania · USUniversity of Tübingen · DE

Funding

PHS HHS 234-2005-370011C
6 · The paper itself

Abstract

objectiveTo determine whether kidney transplants performed during a weekend had worse outcomes than those performed during weekdays.

designRetrospective national database study.

settingUnited Network for Organ Sharing database of the USA.

participants136,715 adult recipients of deceased donor single organ kidney transplants in the USA between 4/1994 and 9/2010.

main outcome measuresThe primary outcomes were patient survival and death-censored and overall allograft survival. Secondary outcomes included initial length of hospital stay after transplantation, delayed allograft function, acute rejection within the first year of transplant, and patient and allograft survival at 1 month and at 1 year after transplantation. Cox proportional hazards models were used to evaluate the impact of weekend kidney transplant surgery on primary and secondary outcomes, adjusting for multiple covariates.

resultsAmong the 136,715 kidney recipients, 72.5% underwent transplantation during a regular weekday (Monday-Friday) and 27.5% during a weekend (Saturday-Sunday). No significant association was noted between weekend transplant status and patient survival, death-censored allograft survival or overall allograft survival in the adjusted analyses (HR 1.01 (95% CI 0.92 to 1.04), 1.012 (95% CI 0.99 to 1.034), 1.012 (95% CI 0.984 to 1.04), respectively). In addition, no significant association was noted between weekend transplant status and the secondary outcomes of patient and graft survival at 1 month and 1 year, delayed allograft function or acute rejection within the first year. Results remained consistent across all definitions of weekend status.

conclusionsThe outcomes for deceased donor kidney transplantation in the USA are not affected by the day of surgery. The operationalisation of deceased donor kidney transplantation may provide a model for other surgeries or emergency procedures that occur over the weekend, and may help reduce length of hospital stay and improve outcomes.

Indexed as

Time FactorsAdultDatabases, FactualFemaleGraft SurvivalHumansKaplan-Meier EstimateKidney TransplantationLength of StayMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CareProportional Hazards ModelsRetrospective StudiesTreatment Outcomegraft survivalkidney transplantationpatient survivalweekend effect

Identifiers

PMID27056590
PMCPMC4838691
OpenAlexW2323864916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.