ReviewDevelopment genes and evolution2016
The insect central complex as model for heterochronic brain development-background, concepts, and tools.
Review in Development genes and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- Anatomical changes of Tenebrio molitor and Tribolium castaneum during complete metamorphosis.Cell and tissue research · 2024Article
- Olfactory navigation in arthropods.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Review
- Review
- Shaking hands is a homeodomain transcription factor that controls axon outgrowth of central complex neurons in the insect model Tribolium.Development (Cambridge, England) · 2021Article
- Sequence heterochrony led to a gain of functionality in an immature stage of the central complex: A fly-beetle insight.PLoS biology · 2020Article
- Adult neurogenesis in the mushroom bodies of red flour beetles (Tribolium castaneum, HERBST) is influenced by the olfactory environment.Scientific reports · 2020Article
- Article
- An ancestral apical brain region contributes to the central complex under the control ofeLife · 2019Article
- Development of the anterior visual input pathway to the Drosophila central complex.The Journal of comparative neurology · 2017Article
- A key role forDevelopment (Cambridge, England) · 2017Article
- A conserved plan for wiring up the fan-shaped body in the grasshopper and Drosophila.Development genes and evolution · 2017Article
- Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos.Journal of visualized experiments : JoVE · 2017Article
- Development of the Neurochemical Architecture of the Central Complex.Frontiers in behavioral neuroscience · 2016Review
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10 authors.
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Abstract
The adult insect brain is composed of neuropils present in most taxa. However, the relative size, shape, and developmental timing differ between species. This diversity of adult insect brain morphology has been extensively described while the genetic mechanisms of brain development are studied predominantly in Drosophila melanogaster. However, it has remained enigmatic what cellular and genetic mechanisms underlie the evolution of neuropil diversity or heterochronic development. In this perspective paper, we propose a novel approach to study these questions. We suggest using genome editing to mark homologous neural cells in the fly D. melanogaster, the beetle Tribolium castaneum, and the Mediterranean field cricket Gryllus bimaculatus to investigate developmental differences leading to brain diversification. One interesting aspect is the heterochrony observed in central complex development. Ancestrally, the central complex is formed during embryogenesis (as in Gryllus) but in Drosophila, it arises during late larval and metamorphic stages. In Tribolium, it forms partially during embryogenesis. Finally, we present tools for brain research in Tribolium including 3D reconstruction and immunohistochemistry data of first instar brains and the generation of transgenic brain imaging lines. Further, we characterize reporter lines labeling the mushroom bodies and reflecting the expression of the neuroblast marker gene Tc-asense, respectively.
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