Evidence map›Paper›PMID 27056273›Full record

ArticleInternational journal for parasitology2016

Identification of new markers for the Schistosoma mansoni vitelline lineage.

Jipeng Wang, James J Collins

Abstract read
In one paragraph

Article in International journal for parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Chemical modulation ofWellcome open research · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The effect of fs800 on female egg production in Schistosoma mansoni.Molecular and biochemical parasitology · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. A single-cell RNA-seq atlas ofScience (New York, N.Y.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jipeng WangDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
James J CollinsDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: JamesJ.Collins@UTSouthwestern.edu.

Funding

The Biology of Stem Cells in the Human Parasite Schistosoma MansoniR01AI121037 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI COLLINS, JAMES J · 2016 to 2025
$4.4M
NIAID NIH HHS HHSN272201000005CNIAID NIH HHS HHSN272201000005INIAID NIH HHS R01 AI121037Wellcome TrustWellcome Trust 107475/Z/15/Z
6 · The paper itself

Abstract

Schistosomes cause significant morbidity and mortality in millions of the world's poorest people. While parasite egg-induced inflammation is the primary driver of host pathology, relatively little is known at the molecular level about the organ systems that participate in schistosome egg production (i.e., testes, ovaries and vitellaria). Here we use transcriptional profiling and in situ hybridization to characterise the vitellarium of Schistosoma mansoni. We uncovered several previously uncharacterised vitellaria-specific factors and defined molecular markers for various stages in the vitellocyte differentiation process. These data provide the framework for future in-depth molecular studies exploring the biology of this important parasite organ.

Indexed as

AnimalsBiomarkersCell DifferentiationFemaleGene Expression ProfilingIn Situ Hybridization, FluorescenceRNA, HelminthSchistosoma mansoniSequence Analysis, RNAStem CellsTranscription, GeneticVitellinsBiomarkersRNA, HelminthVitellinsReproducitonSchistosomaStem cellVitellaria

Identifiers

PMID27056273
PMCPMC4917872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.