Evidence map›Paper›PMID 27056207›Full record

Trial reportSingapore medical journal2017

A randomised controlled trial investigating the analgesic efficacy of transversus abdominis plane block for adult laparoscopic appendicectomy.

Darell Alexander Tupper-Carey, Shahridan Mohd Fathil, Yin Kiat Glenn Tan, Yuk Man Kan, Chern Yuen Cheong, Fahad Javaid Siddiqui, Pryseley Nkouibert Assam

3 registry-linked trialsOpen access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Singapore medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04031196 nacompletednot on this mapstarted 2018, after this paper: background citation

Ultrasound-guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendicectomy: A Randomized Clinical Study

TypeinterventionalSponsorZagazig UniversityRan2018 to 2019Enrolled34ConditionsChildren, AppendicitisArmsQLB, TAP block
NCT05310266 nacompletednot on this mapstarted 2020, after this paper: background citation

Ultrasound-guided Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Appendectomy: A Prospective, Randomized, Controlled Clinical Study

TypeinterventionalSponsorBakirkoy Dr. Sadi Konuk Research and Training HospitalRan2020 to 2022Enrolled168ConditionsPost Operative Pain, Appendicitis Acute, SurgeryArmsTransversus abdominis plane block, Quadratus Lumborum Block
NCT06088082 phase3unknown statusnot on this mapstarted 2023, after this paper: background citation

"Analgesic Efficacy of Combined Transversus Abdominis Plane Block and Posterior Rectus Sheath Block in Patients Undergoing Laparoscopic Appendectomy"

TypeinterventionalSponsorKing Saud Medical CityRan2023 to 2024Enrolled100ConditionsERASArmsBupivacaine Hydrochloride
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Pain management in abdominal surgery.Langenbeck's archives of surgery · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Darell Alexander Tupper-CareyDepartment of Anaesthesia, Ng Teng Fong General Hospital, JurongHealth, Singapore.
Shahridan Mohd FathilDepartment of Anaesthesia, Ng Teng Fong General Hospital, JurongHealth, Singapore.
Yin Kiat Glenn TanDepartment of Anaesthesia, Ng Teng Fong General Hospital, JurongHealth, Singapore.
Yuk Man KanDepartment of Surgery, Ng Teng Fong General Hospital, JurongHealth, Singapore.
Chern Yuen CheongDepartment of Surgery, Ng Teng Fong General Hospital, JurongHealth, Singapore.
Fahad Javaid SiddiquiCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Pryseley Nkouibert AssamCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Ng Teng Fong General Hospital · SGDuke-NUS Medical School · SGSingapore Clinical Research Institute · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe conducted a single-centre, prospective randomised clinical trial to investigate the analgesic efficacy of transversus abdominis plane (TAP) block in adult patients undergoing laparoscopic appendicectomy.

methodsPatients undergoing urgent laparoscopic appendicectomy under general anaesthesia alone (control group) and general anaesthesia supplemented by TAP block (TAP intervention group) were compared. All patients received a multimodal analgesia regime, which included postoperative morphine via a patient-controlled analgesia device. The primary endpoints were morphine consumption at 12 hours and 24 hours postoperatively. Secondary endpoints included pain scores, incidence of nausea and vomiting, and time to hospital discharge. A total of 58 patients were recruited, with 29 patients in each group.

resultsMean postoperative morphine consumption at 12 hours (control group: 11.45 ± 7.64 mg, TAP intervention group: 9.79 ± 8.09 mg; p = 0.4264) and 24 hours (control group: 13.38 ± 8.72 mg, TAP intervention group: 11.31 ± 8.66 mg; p = 0.3686) for the control and TAP intervention groups were not statistically different. Secondary outcomes were also not different between the two groups. Length of stay in the post-anaesthesia care unit was significantly shorter for the TAP intervention group, with a trend toward faster hospital discharge being observed.

conclusionTAP block, a regional anaesthetic procedure performed immediately prior to skin incision for laparoscopic appendicectomy, did not significantly improve postoperative analgesia outcomes.

Indexed as

AppendectomyAbdominal MusclesAdultAnalgesia, Patient-ControlledFemaleHumansLaparoscopyMaleMorphineNerve BlockPostoperative PainMorphinelaparoscopic appendicectomypostoperative analgesiaregional anaesthesiatransversus abdominis plane block

Identifiers

PMID27056207
PMCPMC5563528
OpenAlexW2322681941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.