SynthesisEnvironmental science and pollution research international2016
Body burden of persistent organic pollutants on hypertension: a meta-analysis.
Synthesis in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Association between polychlorinated biphenyls and hypertension risk: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.Annals of global health · 2024Pooled it
- Correlation between Prenatal Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Infant Birth Outcomes: A Meta-Analysis and an Experimental Study.International journal of environmental research and public health · 2017Pooled it
- Implications of Endocrine-Disrupting Chemicals for Human Health and Effective Methods for Prevention and Reduction.Toxics · 2026Review
- Personal Care Products and Incident Hypertension: Prospective Cohort Study of U.S. Women.medRxiv : the preprint server for health sciences · 2026Article
- Male infertility and risk of cardiometabolic conditions: a population-based cohort study.Human reproduction (Oxford, England) · 2026Article
- Endocrine-disrupting chemicals exposure: cardiometabolic health risk in humans.Cardiovascular diabetology · 2025Review
- The role of per- and polyfluoroalkyl substances in cognitive impairment and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Metabolic Signatures in Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures to Blood Pressure Five Years After Bariatric Surgery Among Adolescents.Environmental science & technology · 2025Article
- Pathophysiological Features of Remodeling in Vascular Diseases: Impact of Inhibitor of DNA-Binding/Differentiation-3 and Estrogenic Endocrine Disruptors.Medical sciences (Basel, Switzerland) · 2024Review
- Environmental Pollution and Cardiovascular Disease: Part 2 of 2: Soil, Water, and Other Forms of Pollution.JACC. Advances · 2024Review
- OMICs Signatures Linking Persistent Organic Pollutants to Cardiovascular Disease in the Swedish Mammography Cohort.Environmental science & technology · 2024Article
- The association between carbon and nitrogen stable isotope ratios of human hair and hypertension.Clinical hypertension · 2023Article
- A meta-analysis of randomized controlled studies on the hepatoxicity induced by polybrominated diphenyl ethers (PBDEs) in rats and mice.Current research in toxicology · 2023Article
- The Health Status of Hispanic Agricultural Workers in Georgia and Florida.Journal of immigrant and minority health · 2022Article
- The association between organophosphate insecticides and blood pressure dysregulation: NHANES 2013-2014.Environmental health : a global access science source · 2022Article
- Article
- PCB126 induced toxic actions on liver energy metabolism is mediated by AhR in rats.Toxicology · 2022Article
- Role of environmental toxicants in the development of hypertensive and cardiovascular diseases.Toxicology reports · 2022Review
- Prenatal exposure to persistent organic pollutants and markers of obesity and cardiometabolic risk in Spanish adolescents.Environment international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Except the known risk factors for hypertension, several studies have suggested that exposure to persistent organic pollutants (POPs), endocrine disrupting chemicals, could be associated with an increased risk of hypertension. In this study, we performed a meta-analysis to summarize the existing epidemiological studies to investigate the association between POPs concentration and risk of hypertension. Based on comprehensive literature search results (PubMed, EMBASE, and KoreaMed), a meta-analysis of 11 articles was performed using a random-effects model. While we observed no significant association between the sum of non-dioxin-like PCBs and the risk of hypertension (OR = 1.00; 95 % CI 0.89, 1.12), the sum of dioxin-like PCBs was associated with a significantly increased risk of hypertension (OR = 1.45; 95 % CI 1.00, 2.12). High p,p'-DDE level was also significantly associated with the increased risk of hypertension. When subgroup analyses were carried out for studies which analyzed POPs concentrations using high-resolution gas chromatography/high-resolution mass spectrometry, the overall pooled estimate ORs increased with decreased heterogeneity, providing it as a possible heterogeneity source (OR = 1.36; 95 % CI 1.21, 1.52; I (2) = 42.8 %; p = 0.045). This study suggested that the concentration of certain POPs, especially dioxin-related compounds, was associated with the risk of hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.