Evidence map›Paper›PMID 27055775›Full record

ArticleCBE life sciences education2016

Development of the Central Dogma Concept Inventory (CDCI) Assessment Tool.

Dina L Newman, Christopher W Snyder, J Nick Fisk, L Kate Wright

Open access · hybridAbstract read
In one paragraph

Article in CBE life sciences education, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
33.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Call for collaboration: Drafting a concept inventory for assessing neuroscience courses and curriculum.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2025
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  4. Design principles for molecular animation.Frontiers in bioinformatics · 2024
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  7. Teaching meiosis with the DNA triangle framework: A classroom activity that changes how students think about chromosomes.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2022
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  12. Physical models can provide superior learning opportunities beyond the benefits of active engagements.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2018
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  19. CBE life sciences education · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dina L NewmanThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623 dina.newman@rit.edu.
Christopher W SnyderThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623.
J Nick FiskThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623.
L Kate WrightThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623.
Rochester Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientific teaching requires scientifically constructed, field-tested instruments to accurately evaluate student thinking and gauge teacher effectiveness. We have developed a 23-question, multiple select-format assessment of student understanding of the essential concepts of the central dogma of molecular biology that is appropriate for all levels of undergraduate biology. Questions for the Central Dogma Concept Inventory (CDCI) tool were developed and iteratively revised based on student language and review by experts. The ability of the CDCI to discriminate between levels of understanding of the central dogma is supported by field testing (N= 54), and large-scale beta testing (N= 1733). Performance on the assessment increased with experience in biology; scores covered a broad range and showed no ceiling effect, even with senior biology majors, and pre/posttesting of a single class focused on the central dogma showed significant improvement. The multiple-select format reduces the chances of correct answers by random guessing, allows students at different levels to exhibit the extent of their knowledge, and provides deeper insight into the complexity of student thinking on each theme. To date, the CDCI is the first tool dedicated to measuring student thinking about the central dogma of molecular biology, and version 5 is ready to use.

Indexed as

Educational MeasurementHumansMolecular BiologyPilot ProjectsStudents

Identifiers

PMID27055775
PMCPMC4909347
OpenAlexW2318902520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.