ArticleSleep & breathing = Schlaf & Atmung2016
Long-term CPAP treatment improves asthma control in patients with asthma and obstructive sleep apnoea.
Article in Sleep & breathing = Schlaf & Atmung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Association of Obstructive Sleep Apnea with Asthma: A Meta-Analysis.Scientific reports · 2017Pooled it
- Prevalence and Risk Factors of Sleep Disordered Breathing in School-Aged Children with Bronchopulmonary Dysplasia.Pediatric allergy, immunology, and pulmonology · 2026Article
- Asthma and Obstructive Sleep Apnea Overlap Syndrome Identifies a Phenotype of Sleep Instability and Increased Psychological Burden.Life (Basel, Switzerland) · 2026Article
- Clinical and Sleep Characteristics and the Effect of CPAP Treatment on Obese Patients with Obstructive Sleep Apnea and Asthma-A Retrospective Study.Healthcare (Basel, Switzerland) · 2025Article
- Obstructive Sleep Apnea Is Associated with Worsened Hospital Outcomes in Children Hospitalized with Asthma.Children (Basel, Switzerland) · 2024Article
- The CORE syndrome: an overlap of severe asthma, obstructive sleep apnea, rhinosinusitis, and esophageal reflux.Sleep & breathing = Schlaf & Atmung · 2024Article
- Asthma and Sleep-disordered Breathing Overlap in School-aged Children.Annals of the American Thoracic Society · 2024Article
- The Effect of Simulated Obstructive Apneas on Mechanical Characteristics of Lower Airways in Individuals with Asthma.Annals of biomedical engineering · 2024Article
- Revisiting Asthma Obstructive Sleep Apnea Overlap: Current Knowledge and Future Needs.Journal of clinical medicine · 2023Review
- Chronic intermittent hypoxia increases airway hyperresponsiveness during house dust mites exposures in rats.Respiratory research · 2023Article
- Low arousal threshold: a common pathophysiological trait in patients with obstructive sleep apnea syndrome and asthma.Sleep & breathing = Schlaf & Atmung · 2023Article
- Differences in L-arginine metabolism and asthma morbidity among asthma patients with and without obstructive sleep apnea.Respiratory research · 2022Article
- The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children.The journal of allergy and clinical immunology. In practice · 2022Article
- Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD.The journal of allergy and clinical immunology. In practice · 2021Review
- Impact of comorbid conditions on asthmatic adults and children.NPJ primary care respiratory medicine · 2020Review
- Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?American journal of respiratory and critical care medicine · 2020Review
- Τhe Co-Existence of Obstructive Sleep Apnea and Bronchial Asthma: Revelation of a New Asthma Phenotype?Journal of clinical medicine · 2019Review
- Polysomnographic variables in Alternate overlap syndrome: data from sleep heart health study.Journal of community hospital internal medicine perspectives · 2019Article
- Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBoth asthma and obstructive sleep apnoea cause sleep disturbance, daytime sleepiness and diminished quality of life. Continuous positive airway pressure (CPAP) is efficient in reducing symptoms related to sleep apnoea. Here we report the impact of long-term use of CPAP on asthma symptoms.
methodsA survey questionnaire was distributed to all of our obstructive sleep apnoea patients with CPAP therapy in 2013. We used the Finnish version of the Asthma Control Test™ (ACT) and a visual analogue scale (0 = no symptoms, 100 = severe asthma symptoms). Asthma was defined as self-reported physician-diagnosed disease and a special reimbursement for asthma medication by the Social Insurance Institution.
resultsWe sent 2577 questionnaires and received 1586 answers (61 %). One hundred ninety-seven patients were asthmatics with a prevalence of asthma among CPAP users of 13 %. We studied 152 patients (58 females) whose CPAP therapy was initiated after starting asthma medication. Their mean (SD) age was 62 (10) years, duration of CPAP 5.7 (4.7) years and their CPAP daily use was 6.3 (2.4) h. Self-reported asthma severity decreased significantly from 48.3 (29.6) to 33.1 (27.4) (p < 0.001), and ACT score increased significantly from 15.35 (5.3) to 19.8 (4.6) (p < 0.001) without a significant change in the body mass index (BMI). The percentage of patients using rescue medication daily reduced from 36 to 8 % with CPAP (P < 0.001).
conclusionsWe noticed a significant decrease in asthma symptoms with long-term use of CPAP in patients with both asthma and obstructive sleep apnoea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.