ArticleThe British journal of radiology2016
Diagnosing venous thromboembolism in pregnancy.
Article in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Computed tomography pulmonary angiographyHaematologica · 2019Pooled it
- Diagnosing Pulmonary Embolism During Pregnancy.Chest · 2025Review
- Pulmonary Considerations for Pregnant Women.Clinics in chest medicine · 2021Review
- Pregnancy-adapted YEARS algorithm: can YEARS do more for pregnant women?Breathe (Sheffield, England) · 2020Article
- EANM guideline for ventilation/perfusion single-photon emission computed tomography (SPECT) for diagnosis of pulmonary embolism and beyond.European journal of nuclear medicine and molecular imaging · 2019Article
- Pregnancy and Pulmonary Embolism.Clinics in chest medicine · 2018Review
- Referral Patterns and Diagnostic Yield of Lung Scintigraphy in the Diagnosis of Acute Pulmonary Embolism.Thrombosis · 2017Article
- Investigation of fetal absorbed dose in V/Q scan in three trimesters of pregnancy using Monte Carlo simulation.World journal of nuclear medicineArticle
- Reversible pulmonary artery perfusion abnormalities in the postpartum period as a precursor to the development of pulmonary arterial hypertension.Pulmonary circulationArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe report the imaging outcomes of all pregnant patients referred for suspected thromboembolism over a 43-month period.
methodsWe identified 168 patients who underwent ventilation/perfusion (VQ) single-photon emission CT (SPECT), CT pulmonary angiography (CTPA) or a Doppler ultrasound scan of the lower legs, as well as a control group of 89 non-pregnant age- and sex-matched patients who underwent VQ SPECT during the same period. Imaging outcomes were recorded, and radiation doses were calculated for individual patients.
resultsVQ SPECT and CTPA were equally likely to diagnose pulmonary embolism (PE) in about one patient out of every seven patients investigated. One in three CTPA scans was of suboptimal quality. A Doppler ultrasound examination of the legs will find deep venous thrombosis much less often, in about 1 patient out of every 15 patients investigated. The prevalence of PE in pregnant patients (as diagnosed by VQ SPECT) was similar to that in the non-pregnant, age- and sex-matched control group. The effective dose and the absorbed radiation dose to the maternal breast were lower with VQ SPECT. The foetal dose is comparable for both VQ SPECT and CTPA.
conclusionVQ SPECT and CTPA provide a similar diagnostic yield for diagnosing PE during pregnancy, but VQ SPECT does so with a lower radiation dose to the mother (effective dose and breast dose). ADVANCES IN KNOWLEDGE: Ours is the first report of the diagnostic performance of VQ SPECT, rather than planar VQ scans, in pregnancy in a routine clinical setting.
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