Evidence map›Paper›PMID 27055179›Full record

Trial reportPloS one2016

Disease Burden Due to Herpes Zoster among Population Aged ≥50 Years Old in China: A Community Based Retrospective Survey.

Yan Li, Zhijie An, Dapeng Yin, Yanmin Liu, Zhuoying Huang, Jianfang Xu, Yujie Ma, Qiufeng Tu, Qi Li, Huaqing Wang

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 7 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 7 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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  17. [Application of support vector machine in identifying neuromodulation states in patients with zoster-associated pain].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Yan LiNational immunization program, Chinese center for disease control and prevention, Beijing, China.
Zhijie AnNational immunization program, Chinese center for disease control and prevention, Beijing, China.
Dapeng YinNational immunization program, Chinese center for disease control and prevention, Beijing, China.
Yanmin LiuNational immunization program, Chinese center for disease control and prevention, Beijing, China.
Zhuoying HuangImmunization program department, Shanghai municipal center for disease control and prevention, Shanghai, China.
Jianfang XuImmunization program department, Danyang county center for disease control and prevention, Zhenjiang, Jiangsu, China.
Yujie MaImmunization program department, Heilongjiang provincial center for disease control and prevention, Haerbin, Heilongjiang, China.
Qiufeng TuImmunization program department, Jiangxi provincial center for disease control and prevention, Nanchang, Jiangxi, China.
Qi LiImmunization program department, Hebei provincial center for disease control and prevention, Shijiazhuang, Hebei, China.
Huaqing WangNational immunization program, Chinese center for disease control and prevention, Beijing, China.
Chinese Center For Disease Control and Prevention · CNHebei Provincial Center for Disease Control and Prevention · CNHeilongjiang Center for Tuberculosis Control and Prevention · CNNanchang Center for Disease Control and Prevention · CNShanghai Municipal Center For Disease Control Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo understand the disease burden due to Herpes Zoster (HZ) among people aged ≥50 years old in China and provide baseline data for future similar studies, and provide evidence for development of herpes zoster vaccination strategy.

methodsRetrospective cohort study was conducted in 4 townships and one community. A questionnaire was used to collect information on incidence and cost of HZ among people aged ≥ 50 years old.

resultsThe cumulative incidence rate was 22.6/1,000 among people aged ≥ 50 years old. The average annual incidence rate of HZ was 3.43/1,000 among people aged ≥ 50 years old in 2010-2012. Cumulative incidence and average annual incidence rate increased with age: the cumulative incidence of HZ among people aged ≥ 80 years old was 3.34 times of that among 50-years old (52.3/1000 vs 15.7/1,000); average annual incidence rate rises from 2.66/1,000 among 50-years old to 8.55/1,000 among 80-year old. Cumulative incidence and average annual incidence rate for females were higher than that for males (cumulative incidence, 26.5/1000 vs 18.7/1,000; annual incidence rate, 3.95/1000 vs 2.89/1,000). Cumulative incidence and average annual incidence rate in urban were higher than in rural (cumulative incidence, 39.5/1000 vs 17.2/1,000; annual incidence rate, 7.65/1000 vs 2.06/1,000). The hospitalization rate of HZ was 4.53%. And with the increase of age, the rate has an increasing trend. HZ costs 945,709.5 RMB in total, corresponding to 840.6 RMB per patient with a median cost of 385 RMB (interquartile range 171.7-795.6). Factors associated with cost included the first onset year, area, whether hospitalized and whether sequelae left.

conclusionIncidence rate, complications, hospitalization rate and average cost of HZ increase with age. We recommend that the HZ vaccinations should target people aged ≥50 years old if Zoster vaccine is licensed in China.

Indexed as

Rural PopulationSurveys and QuestionnairesUrban PopulationAgedAged, 80 and overChinaFemaleHerpes ZosterHumansIncidenceMaleMiddle AgedRetrospective StudiesSex Factors

Identifiers

PMID27055179
PMCPMC4824529
OpenAlexW2327632813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.