Evidence map›Paper›PMID 27054153›Full record

ArticleData in brief2016

Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: a proteomic dataset from formalin-fixed archival samples.

Alessandro Tanca, Maria Filippa Addis, Salvatore Pisanu, Marcello Abbondio, Daniela Pagnozzi, Albino Eccher, Guido Rindi, Paolo Cossu-Rocca, Sergio Uzzau, Giuseppe Fanciulli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Alessandro TancaPorto Conte Ricerche, Tramariglio, Alghero, Italy.
Maria Filippa AddisPorto Conte Ricerche, Tramariglio, Alghero, Italy.
Salvatore PisanuPorto Conte Ricerche, Tramariglio, Alghero, Italy.
Marcello AbbondioPorto Conte Ricerche, Tramariglio, Alghero, Italy.
Daniela PagnozziPorto Conte Ricerche, Tramariglio, Alghero, Italy.
Albino EccherU.O. di Anatomia Patologica, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Guido RindiIstituto di Anatomia Patologica, Università Cattolica del Sacro Cuore-Policlinico A. Gemelli, Rome, Italy.
Paolo Cossu-RoccaU.O. di Anatomia Patologica, Azienda Sanitaria Locale di Olbia, Olbia, Italy.
Sergio UzzauPorto Conte Ricerche, Tramariglio, Alghero, Italy; Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.
Giuseppe FanciulliNET Unit, Dipartimento di Medicina Clinica e Sperimentale, Università di Sassari, AOU Sassari, Sassari, Italy.
Consorzio Futuro in Ricerca · ITUniversity of Sassari · ITASL Roma · ITAzienda Ospedaliera Universitaria Integrata Verona · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR <1%. MS data are available in the PeptideAtlas repository at http://www.peptideatlas.org/PASS/PASS00375.

Indexed as

Archival tissuesFFPEMass spectrometryNeuroendocrine tumorsProteomics

Identifiers

PMID27054153
PMCPMC4796709
OpenAlexW2293898913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.