Evidence map›Paper›PMID 27054034›Full record

ArticleAnnals of medicine and surgery (2012)2016

Effectiveness and properties of the biological prosthesis Permacol™ in pediatric surgery: A large single center experience.

Claudia Filisetti, Sara Costanzo, Federica Marinoni, Claudio Vella, Catherine Klercy, Giovanna Riccipetitoni

Abstract read
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Article in Annals of medicine and surgery (2012), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Claudia Filisetti"V. Buzzi" Children Hospital, Milan, Italy; Department of Surgery, PhD School of Experimental Medicine, University of Pavia, Italy.
Sara Costanzo"V. Buzzi" Children Hospital, Milan, Italy.
Federica Marinoni"V. Buzzi" Children Hospital, Milan, Italy.
Claudio Vella"V. Buzzi" Children Hospital, Milan, Italy.
Catherine KlercyServizio di Biometria e Statistica, Direzione Scientifica, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Giovanna Riccipetitoni"V. Buzzi" Children Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of prosthetic patches of non-absorbable materials represents a valid tool in the treatment of abdominal wall and diaphragmatic defects in pediatric age. In recent years research has developed biological dermal scaffolds made from a sheet of acellular matrix that can provide the desired support and reduce the occurrence of complications from non-absorbable implant. We present our experience and a systematic review to evaluate the use of biologic prosthesis for abdominal wall closure in pediatric patients.

methodsThe study from January 2009 to January 2015 involved 20 patients treated with Permacol™ implant. We observed postoperative complications only in patients treated for abdominal wall closure, which is the major indication for the use of Permacol™. We conducted a systematic review and meta-analysis (according to PRISMA) on PubMed/Medline, Scopus and EMBASE regarding the use of biological prosthesis in pediatric population considering the incidence of complications as the primary outcome.

results3/20 patients experienced complications: 2 patients with skin necrosis healed conservatively and 1 of them developed laparocele. Thus only 1 patient with incisional hernia had significant surgery complication. In patients who were permanently implanted with Permacol™ it has not determined adverse reactions with optimal functional outcome.

conclusionsIn accordance with the few data (case reports and case series) reported in literature about pediatric patients, our experience in different pathologies and applications has shown the effectiveness of Permacol™, in particular for the non-occurrence of infections, that often affect the use of prosthesis.

Indexed as

Abdominal wallBiological prosthesisPediatric patientsPermacol

Identifiers

PMID27054034
PMCPMC4802399

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