Evidence map›Paper›PMID 27053858›Full record

Observational studyWorld journal of gastroenterology2016

Prevalence of and risk factors for non-alcoholic fatty liver disease in a Chinese population: An 8-year follow-up study.

Zhen-Ya Lu, Zhou Shao, Ya-Li Li, Muhuyati Wulasihan, Xin-Hua Chen

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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  17. [Etiological analysis of hepatopathy of unknown etiology in 470 cases undergoing routine liver biopsy examination].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhen-Ya LuZhen-Ya Lu, Department of Internal Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Zhou ShaoZhen-Ya Lu, Department of Internal Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Ya-Li LiZhen-Ya Lu, Department of Internal Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Muhuyati WulasihanZhen-Ya Lu, Department of Internal Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
Xin-Hua ChenZhen-Ya Lu, Department of Internal Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
First Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the prevalence of and risk factors for non-alcoholic fatty liver disease (NAFLD) in a Chinese population.

methodsA total of 1948 adults from China was followed for 8 years. A cross-sectional study was performed to investigate the prevalence of NAFLD at baseline, and then the participants were followed for 8 years to investigate risk factors for the development of NAFLD.

resultsA total of 1948 participants were enrolled at baseline, of whom 691 were diagnosed with NAFLD. During the 8-year follow-up, 337 baseline NAFLD-free participants developed NAFLD. They had a greater increase in body mass index (BMI), serum uric acid, fasting plasma glucose, very low-density lipoprotein cholesterol and a considerable decrease in high-density lipoprotein cholesterol. 123 participants who had NAFLD at baseline lost NAFLD during the 8-year follow-up period. They had a greater decrease in BMI, fasting plasma glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol, alanine aminotransferase, aspartate aminotransferase, and γ-glutamyl transpeptidase.

conclusionNAFLD is prevalent in Chinese population with a rapidly increasing tendency. It can be reversed when patients lose their weight, control their hyperlipidemia and hyperglycemia, and reduce the liver enzyme levels.

Indexed as

Urban HealthAdultAgedBiomarkersBlood GlucoseBody Mass IndexChinaCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDyslipidemiasFemaleFollow-Up StudiesHumansHyperglycemiaHyperuricemiaBiomarkersBlood GlucoseCholesterol, HDLCholesterol, LDLTriglyceridesUric AcidFollow-upNon-alcoholic fatty liver diseasePrevalenceRisk factors

Identifiers

PMID27053858
PMCPMC4814652
OpenAlexW2317079235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.