ArticleThe Journal of infectious diseases2016
Seminal HIV-1 RNA Detection in Heterosexual African Men Initiating Antiretroviral Therapy.
Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Decay kinetics of HIV-1-RNA in seminal plasma with dolutegravir/lamivudine versus dolutegravir plus emtricitabine/tenofovir alafenamide in treatment-naive people living with HIV.The Journal of antimicrobial chemotherapy · 2023Trial
- Characterization and distribution of HIV-infected cells in semen.Emerging microbes & infections · 2022Article
- HIV-Related Stigma Reduction in the Era of Undetectable Equals Untransmittable: The South Korean Perspective.Infection & chemotherapy · 2021Review
- Detection of HIV-1 viral load in tears of HIV/AIDS patients.Infection · 2020Article
- Detectable HIV-1 in semen in individuals with very low blood viral loads.Virology journal · 2020Article
- Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study.Lancet (London, England) · 2019Observational
- Cost-effectiveness of preexposure prophylaxis for HIV prevention for conception in the United States.AIDS (London, England) · 2018Article
- Effects of Antiretroviral Therapy to Prevent HIV Transmission to Women in Couples Attempting Conception When the Man Has HIV Infection - United States, 2017.MMWR. Morbidity and mortality weekly report · 2017Article
- Detectable HIV-RNA in semen of HIV controllers.PloS one · 2017Article
- Exploring the anatomical HIV reservoirs: role of the testicular tissue.AIDS (London, England) · 2016Article
- Semen as the Way Forward to Understand HIV-1 Transmission.The Journal of infectious diseases · 2016Article
- Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundIntermittent shedding of human immunodeficiency virus type 1 (HIV) in semen occurs despite effective antiretroviral therapy (ART) and suppressed blood HIV-1 RNA levels.
methodsWe assessed the frequency, magnitude, and correlates of seminal HIV-1 RNA shedding in HIV-1-infected African men initiating ART.
resultsSeminal HIV-1 RNA was detected in 24% (37 of 155), 10% (5 of 49), and 11% (8 of 70) of samples collected 0-3, 4-6, and >6 months after ART initiation. When blood HIV-1 levels were suppressed, seminal HIV-1 RNA was detected in 8% (16 of 195), and 82% (13 of 16) had an HIV-1 RNA load of < 1000 copies/mL.
conclusionsSeminal HIV-1 RNA shedding was infrequent and present at low levels in HIV-1-infected African men with suppressed blood HIV-1 RNA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.