Evidence map›Paper›PMID 27053568›Full record

ArticleComparative medicine2016

Serum Vitamin D Concentrations in Baboons (Papio spp.) during Pregnancy and Obesity.

Natalia E Schlabritz-Loutsevitch, Anthony G Comuzzie, Michael M Mahaney, Gene B Hubbard, Edward J Dick, Mehmet Kocak, Sonali Gupta, Maira Carrillo, Mauro Schenone, Arnold Postlethwaite and 1 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Comparative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.American journal of physiology. Endocrinology and metabolism · 2019
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Natalia E Schlabritz-LoutsevitchTexas Tech University HSC School of Medicine at the Permian Basin, Odessa, Texas, USA. Natalia.schlabritz-lutsevich@ttuhsc.edu.
Anthony G ComuzzieDepartments of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Michael M MahaneyThe University of Texas Rio Grande Valley, Brownsville, Texas, USA.
Gene B HubbardDepartment of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Edward J DickDepartments of Pathology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Mehmet KocakDivision of Biostatistics, Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, USA.
Sonali GuptaDepartment of Obstetrics and Gynecology; University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Maira CarrilloTexas Tech University HSC School of Medicine at the Permian Basin, Odessa, Texas.
Mauro SchenoneDepartment of Obstetrics and Gynecology; University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Arnold PostlethwaiteDivision of Connective Tissue Diseases, Department of Medicine, University of Tennessee Health Science Center, and Department of Veterans Affairs Medical Center, Memphis, Tennessee, USA.
Andrzej SlominskiDepartment of Dermatology and Pathology, VA Medical Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
The University of Texas Health Science Center at San Antonio · USThe University of Texas Rio Grande Valley · USUniversity of Tennessee Health Science Center · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
WNV REPLIVAX VACCINE IN NON-HUMAN PRIMATESP51RR013986 · NCRR · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI GAUDUIN, MARIE-CLAIRE ELISABETH · 1999 to 2011
$79.1M
PARTURITION AND FETAL PRIMATE HYPOTHALAMIC FUNCTIONP01HD021350 · NICHD · UNIVERSITY OF WYOMING · PI COX, LAURA A · 1987 to 2018
$19.9M
Novel Biosynthetic Pathway for Secosteroids and the SkinR01AR052190 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI POSTLETHWAITE, ARNOLD E, SLOMINSKI, ANDRZEJ T · 2006 to 2013
$2.2M
Role of Exogenous Melatonin in Skin BiologyR01AR056666 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2011 to 2015
$1.6M
EXTRAMURAL RES FACILITIES CONSTRC06RR015456 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.1M
Mechanism of action of 20-hydroxyvitamin D3 in dermal fibroblastsR21AR066505 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2014 to 2015
$355k
Discovery of tissue-selective, nonhypercalcemic VDR modulators for RA treatmentR21AR063242 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LI, WEI, MILLER, DUANE D · 2013 to 2014
$351k
BABOON F-CAGE FACILITY FOR PRIMATE RESEARCH CENTERC06RR014578 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 1999 to 1999
–
NCRR NIH HHS C06 RR014578NCRR NIH HHS C06 RR015456NCRR NIH HHS P51 RR013986NIAMS NIH HHS 1R21AR063242-01A1NIAMS NIH HHS 2R01AR052190NIAMS NIH HHS R01 AR052190NIAMS NIH HHS R01 AR056666NIAMS NIH HHS R21 AR063242NIAMS NIH HHS R21 AR066505NIAMS NIH HHS R21AR0665051NICHD NIH HHS HD21350NICHD NIH HHS P01 HD021350NIH HHS P51 OD011133
6 · The paper itself

Abstract

Obesity is associated with vitamin D deficiency, which can lead to serious problems during pregnancy. However, the mechanisms of the deficiency and guidelines for vitamin D supplementation during pregnancy are not established yet, and variations in environmental exposures combined with the difficulties of performing research in pregnant women are obstacles in the evaluation of vitamin D metabolism. Baboons (Papio spp.) are an excellent, well-established model for reproductive research and represent a unique opportunity to study vitamin D metabolism in a controlled environment. This study used secondary data and specimen analysis as well as a novel experimental design to evaluate pregnant and nonpregnant baboons that were or were not exposed to sunlight while they were obese and after weight reduction. Daily D3 intake was 71% higher in nonpregnant obese baboons than in their nonobese counterparts, but serum vitamin D concentrations did not differ between these populations. In addition, serum 25-hydroxyvitamin D concentrations correlated negatively with the obesity index. This report is the first to show the effect of obesity and pregnancy on vitamin D concentrations in a NHP population. These data underline the importance of adequate vitamin D supplementation in obese animals.

Indexed as

PapioVitamin D DeficiencyAnimalsFemaleHousing, AnimalHumansModels, AnimalObesityPregnancyPregnancy, AnimalVitamin DVitamins25-hydroxyvitamin DVitamin DVitamins

Identifiers

PMID27053568
PMCPMC4825963
OpenAlexW2336103437

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.