Evidence map›Paper›PMID 27053555›Full record

ReviewJournal of virology2016

Commandeering the Ribosome: Lessons Learned from Dicistroviruses about Translation.

Craig H Kerr, Eric Jan

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Craig H KerrDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.
Eric JanDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada ej@mail.ubc.ca.
University of British Columbia · CA

Funding

CIHR MOP-81244
6 · The paper itself

Abstract

To replicate, all viruses depend entirely on the enslavement of host cell ribosomes for their own advantage. To this end, viruses have evolved a multitude of translational strategies to usurp the ribosome. RNA-based structures known as internal ribosome entry sites (IRESs) are among the most notable mechanisms employed by viruses to seize host ribosomes. In this article, we spotlight the intergenic region IRES from the Dicistroviridae family of viruses and its importance as a model for IRES-dependent translation and in understanding fundamental properties of translation.

Indexed as

Genome, ViralInternal Ribosome Entry SitesAnimalsDicistroviridaeHost-Pathogen InteractionsModels, MolecularProtein BiosynthesisRibosomesRNA, ViralInternal Ribosome Entry SitesRNA, Viral

Identifiers

PMID27053555
PMCPMC4886786
OpenAlexW2329290527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.