Evidence map›Paper›PMID 27053455›Full record

ReviewNature reviews. Cardiology2016

Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis.

Darae Ko, Faisal Rahman, Renate B Schnabel, Xiaoyan Yin, Emelia J Benjamin, Ingrid E Christophersen

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
166citing papers in PubMed, 2 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

166 citing papers in PubMed, 2 syntheses or guidelines pooled it, 336 citations in OpenAlex.

  1. Pooled it
  2. The association of coagulation and atrial fibrillation: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Understanding the Diseased Atria.Physiology (Bethesda, Md.) · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Observational
  16. Cardiovascular-kidney-metabolic interplay in patients with atrial fibrillation receiving direct oral anticoagulants.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  17. Article
  18. Article
  19. Quality of life before and after catheter ablation (pulmonary vein isolation) for atrial fibrillation: Results from the Netherlands Heart Registration.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Article
  20. Review

106 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Darae KoSection of General Internal Medicine, Boston Medical Center, Boston University School of Medicine.
Faisal RahmanDepartment of Internal Medicine, Boston Medical Center, Boston University School of Medicine.
Renate B SchnabelDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, Germany.
Xiaoyan YinBoston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Avenue Framingham, Massachusetts 01702, USA.
Emelia J BenjaminBoston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Avenue Framingham, Massachusetts 01702, USA.
Ingrid E ChristophersenCardiovascular Research Center, Massachusetts General Hospital, 149 13th Street, Charlestown, Massachusetts, 02129, USA.
Boston University · USFramingham Heart Study · USUniversity Medical Center Hamburg-Eppendorf · DEVestre Viken Hospital Trust · NO

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
Boston University Clinical and Translational Science Award (CTSA) Program UL1UL1TR000157 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2012 to 2013
$7.9M
AFGen Consortium: Atrial Fibrillation Genomics to Functional AnalysesR01HL128914 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2015 to 2018
$3.1M
Patterns of Health Care Use, Treatment & Outcomes in Atrial Fibrillation: PATH-AFR01HL102214 · NHLBI · DUKE UNIVERSITY · PI BENJAMIN, EMELIA J., CURTIS, LESLEY H · 2010 to 2012
$1.4M
Risk prediction of atrial fibrillation: clinical, biological and genetic markersRC1HL101056 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ALONSO, ALVARO, BENJAMIN, EMELIA J. · 2009 to 2010
$967k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NCATS NIH HHS UL1 TR000157NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL102214NHLBI NIH HHS R01 HL128914NHLBI NIH HHS RC1 HL101056NHLBI NIH HHS T32 HL007224
6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia in women and men worldwide. During the past century, a range of risk factors has been associated with AF, severe complications from the arrhythmia have been identified, and its prevalence has been increasing steadily. Whereas evidence has accumulated regarding sex-specific differences in coronary heart disease and stroke, the differences between women and men with AF has received less attention. We review the current literature on sex-specific differences in the epidemiology of AF, including incidence, prevalence, risk factors, and genetics, and in the pathophysiology and the clinical presentation and prognosis of patients with this arrhythmia. We highlight current knowledge gaps and areas that warrant future research, which might advance understanding of variation in the risk factors and complications of AF, and ultimately aid more-tailored management of the arrhythmia.

Indexed as

Atrial FibrillationFemaleHumansIncidencePrevalencePrognosisRisk FactorsSex Factors

Identifiers

PMID27053455
PMCPMC5579870
OpenAlexW2322257236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.