Evidence map›Paper›PMID 27053330›Full record

ArticleNeurologia medico-chirurgica2016

Histopathological Features of Brain Arteriovenous Malformations in Japanese Patients.

Yulius Hermanto, Yasushi Takagi, Kazumichi Yoshida, Akira Ishii, Takayuki Kikuchi, Takeshi Funaki, Yohei Mineharu, Susumu Miyamoto

Abstract read
In one paragraph

Article in Neurologia medico-chirurgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yulius HermantoDepartment of Neurosurgery, Kyoto University Graduate School of Medicine.
Yasushi Takagi
Kazumichi Yoshida
Akira Ishii
Takayuki Kikuchi
Takeshi Funaki
Yohei Mineharu
Susumu Miyamoto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical features of high risk brain arteriovenous malformations (BAVMs) are well characterized. However, pathological evidences about the differences that are possessed by high risk patients are still lacking. We reviewed archived routine hematoxylin-eosin specimens from a total of 54 surgical treated BAVMs. The histopathological features in nidus were semi-quantitatively analyzed. We obtained the pathological differences of BAVMs nidus between several clinical features. Among the analyzed pathological features, the significant differences were observed in degree of venous enlargement and intimal hyperplasia. Juvenile, female, diffuse nidus, high Spetzler-Martin grade, and low flow patients had a lesser degree of those parameters compared to adult, male, compact nidus, low Spetzler-Martin grade and high flow patients. High risk profiles of BAVMs patients were well-reflected in the nidus pathology. Therefore, juvenile, female, diffuse nidus, and low flow in Japanese BAVMs patients might have different vascular remodeling process that predispose to higher tendency of hemorrhage.

Indexed as

Asian PeopleAdultFemaleHumansIntracranial Arteriovenous MalformationsJapanMaleRetrospective StudiesRisk FactorsYoung Adult

Identifiers

PMID27053330
PMCPMC4908077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.