Evidence map›Paper›PMID 27053277›Full record

ArticleJournal of the American Pharmacists Association : JAPhA

Prescription opioid use: Patient characteristics and misuse in community pharmacy.

Gerald Cochran, Jennifer L Bacci, Thomas Ylioja, Valerie Hruschak, Sharon Miller, Amy L Seybert, Ralph Tarter

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Pharmacists Association : JAPhA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Managing opioid use disorder in primary care: PEER simplified guideline.Canadian family physician Medecin de famille canadien · 2019
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  11. Implementation of a Pharmacy Follow-Up Program for Dispensed Opioid Medications.International journal of environmental research and public health · 2023
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  20. Brief intervention medication therapy management: Establishment of an opioid misuse intervention model delivered in a community pharmacy.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gerald Cochran
Jennifer L Bacci
Thomas Ylioja
Valerie Hruschak
Sharon Miller
Amy L Seybert
Ralph Tarter

Funding

Longitudinal Modeling of SUD EtiologyK05DA031248 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TARTER, RALPH E · 2012 to 2016
$679k
NIDA NIH HHS K05 DA031248
6 · The paper itself

Abstract

objectivesOpioid pain medication misuse is a major concern for US public health. The purpose of this article is to: 1) describe the demographic and physical, behavioral, and mental health characteristics of patients who fill opioid medications in community pharmacy settings; and 2) describe the extent of opioid medication misuse behaviors among these patients.

designWe recruited and screened a convenience sample of patients with the use of a tablet computer-based assessment protocol that examined behavioral, mental, and physical health. Descriptive and inferential statistics were calculated to describe respondents and their opioid medication misuse and health characteristics.

settingPatients were screened in 2 urban and 2 rural community pharmacies in southwestern Pennsylvania.

participantsSurvey participants were adult patients filling opioid pain medications who were not currently receiving treatment for a cancer diagnosis.

interventionNone.

main outcome measuresValidated screening measures included the Prescription Opioid Misuse Index, Alcohol Use Disorders Identification Test C, Short Form 12, Drug Abuse Screening Test 10, Primary Care Post-traumatic Stress Disorder (PTSD) screen, and the Patient Health Questionnaire 2.

resultsA total of 333 patients were screened (71.2% response rate). Nearly the entire population reported pain above and general health below national norms. Hydrocodone (19.2%) and morphine (20.8%) were found to be the medications with the highest rates of misuse-with hydrocodone having more than 4 times higher odds of misuse compared with other medications (adjusted odds ratio [AOR] 4.48, 95% confidence interval [CI] 1.1-17.4). Patients with positive screens for illicit drug use (AOR 8.07, 95% CI 2.7-24.0), PTSD (AOR 5.88, 95% CI 2.3-14.7), and depression (AOR 2.44, 95% CI 1.0-5.9) also had significantly higher odds for misuse compared with those with negative screening results.

conclusionThese findings provide important foundational data that suggest implementation of regular opioid misuse screening protocols within community pharmacies. Such screening activities could foster a culture of prevention and overall reduction for misuse among patients filling opioid medications in community pharmacies.

Indexed as

AdultAnalgesics, OpioidFemaleHealth StatusHumansMaleMental HealthMiddle AgedOpioid-Related DisordersPainPennsylvaniaPharmaciesPrescription Drug MisuseRural PopulationSocioeconomic FactorsUrban PopulationAnalgesics, Opioid

Identifiers

PMID27053277
PMCPMC4886233
OpenAlexW2303055434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.