Trial reportCephalalgia : an international journal of headache2017
The altered right frontoparietal network functional connectivity in migraine and the modulation effect of treatment.
Trial report in Cephalalgia : an international journal of headache, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Functional brain alterations associated with acupuncture for chronic pain: a scoping review of fMRI studies.Frontiers in neuroscience · 2026Pooled it
- Acupuncture for migraine: a literature review of neuroimaging studies.Frontiers in neurology · 2025Pooled it
- Imaging the brain and vascular reactions to headache treatments: a systematic review.The journal of headache and pain · 2023Pooled it
- Comparative efficacy of acupuncture-related therapy for migraine: A systematic review and network meta-analysis.Frontiers in neurology · 2022Pooled it
- Revealing the Neural Mechanism Underlying the Effects of Acupuncture on Migraine: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- Acupuncture for the prevention of episodic migraine.The Cochrane database of systematic reviews · 2016Pooled it
- Repeated acupuncture treatments modulate amygdala resting state functional connectivity of depressive patients.NeuroImage. Clinical · 2016Trial
- Central executive network-related neuromagnetic abnormalities in chronic and episodic migraine: a resting-state magnetoencephalography study.Frontiers in neuroscience · 2026Article
- Modulation of temporal and occipital cortex by acupuncture in non-menstrual MWoA patients: a rest BOLD fMRI study.BMC complementary medicine and therapies · 2024Article
- Abnormal Functional Connectivity Intra- and Inter-Network in Resting-State Brain Networks of Patients with Toothache.Journal of pain research · 2024Article
- Aberrant dynamic functional network connectivity in vestibular migraine patients without peripheral vestibular lesion.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Bibliometric Analysis of 100 Most Highly Cited Publications on Acupuncture for Migraine.Journal of pain research · 2023Article
- Central Mechanism of Acupuncture Treatment in Patients with Migraine: Study Protocol for Randomized Controlled Neuroimaging Trial.Journal of pain research · 2023Article
- Article
- Efficacy prediction of acupuncture treatment for migraine without aura based on multimodal MRI: A study protocol.Frontiers in neurology · 2022Article
- The cumulative therapeutic effect of acupuncture in patients with migraine without aura: Evidence from dynamic alterations of intrinsic brain activity and effective connectivity.Frontiers in neuroscience · 2022Article
- Neurological mechanism and treatment effects prediction of acupuncture on migraine without aura: Study protocol for a randomized controlled trial.Frontiers in neurology · 2022Article
- Therapeutic applications and potential mechanisms of acupuncture in migraine: A literature review and perspectives.Frontiers in neuroscience · 2022Review
- The brain structure and function abnormalities of migraineurs: A systematic review and neuroimaging meta-analysis.Frontiers in neurology · 2022Review
- The Functional Network of the Visual Cortex Is Altered in Migraine.Vision (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Aims This study aims to investigate the resting-state functional connectivity (rs-fc) of the right frontoparietal network (rFPN) between migraineurs and healthy controls (HCs) in order to determine how the rFPN rs-fc can be modulated by effective treatment. Methods One hundred patients and 46 matched HCs were recruited. Migraineurs were randomized to verum acupuncture, sham acupuncture, and waiting list groups. Resting-state functional magnetic resonance imaging data were collected before and after longitudinal treatments. Independent component analysis was applied in the data analysis. Results We found that migraineurs showed decreased rs-fc between the rFPN and bilateral precuneus compared with HCs. After treatments (real and sham), rFPN rs-fc with the precuneus was significantly reduced. This reduction was associated with headache intensity relief. In order to explore the role of the precuneus in acupuncture modulation, we performed a seed-based rs-fc analysis using the precuneus as a seed and found that the precuneus rs-fc with the bilateral rostral anterior cingulate cortex/medial prefrontal cortex, ventral striatum, and dorsolateral prefrontal cortex was significantly enhanced after treatment. Conclusion Our results suggest that migraineurs are associated with abnormal rFPN rs-fc. An effective treatment, such as acupuncture, may relieve symptoms by strengthening the cognitive adaptation/coping process. Elucidation of the adaptation/coping mechanisms may open up a new window for migraine management.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.