Evidence map›Paper›PMID 27053028›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2016

Self-Reported Sleep Disordered Breathing as Risk Factor for Mortality in the Elderly.

Angeliki Tsapanou, Yian Gu, Deirdre O'Shea, Jennifer Manly, Nicole Schupf, Nikolaos Scarmeas, Yaakov Stern

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Angeliki TsapanouCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York; National and Kapodistrian University of Athens Medical School, Athens, Greece. Electronic address: at2859@cumc.columbia.edu.
Yian GuCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York.
Deirdre O'SheaCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York.
Jennifer ManlyThe Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.
Nicole SchupfCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York; The Division of Epidemiology, Joseph P. Mailman School of Public Health, Columbia University, New York, New York.
Nikolaos ScarmeasCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York; National and Kapodistrian University of Athens Medical School, Athens, Greece; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.
Yaakov SternCognitive Neuroscience Division, Department of Neurology and The Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.
Columbia University · USNational and Kapodistrian University of Athens · GR

Funding

Epidemiology of Biomarkers of Risk and Progression in LOADR01AG037212 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, SCHUPF, NICOLE · 2010 to 2015
$10.1M
Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's DiseaseRF1AG054023 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2016 to 2018
$8.9M
Dietary Factors and Neuroimaging MarkersR00AG042483 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN · 2015 to 2017
$727k
Dietary Factors and Neuroimaging MarkersK99AG042483 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN · 2013 to 2014
$202k
NIA NIH HHS K99 AG042483NIA NIH HHS R00 AG042483NIA NIH HHS R01 AG037212NIA NIH HHS RF1 AG054023
6 · The paper itself

Abstract

backgroundThis study aimed to examine the association between self-reported sleep disordered breathing (SDB) ("awaken short of breath or with a headache") and mortality in a large and ethnically diverse group of community-dwelling elderly people.

methodsA total of 1288 participants, 65 years and older, were examined longitudinally. Sleep problems were estimated using the Medical Outcomes Study Sleep Scale examining sleep disturbance, snoring, awaken short of breath or with a headache, sleep adequacy, and sleep somnolence. Cox regression analysis was used to examine the association between sleep problems and mortality. Age, gender, education, ethnicity, and body mass index were included as covariates. In further analyses we included hypertension, diabetes, heart disease, and stroke as additional covariates.

resultsThe participants were followed for up to 6 years (mean = 2.9, standard deviation = 1.1), and 239 (18.6%) participants died during the follow-up. In unadjusted models, SDB at the initial visit was associated with mortality (hazard ratio [HR] = 1.37; 95% confidence interval [CI] 1.21-1.55; P < .0001). After adjusting for all the covariates, the relationship between SDB and mortality remained significant (HR = 1.48; 95% CI 1.29-1.70; P < .0001). Participants with Caribbean-Hispanic ancestry have higher risk for mortality.

conclusionsOur results suggest that SDB is a risk factor for mortality in a large and ethnically diverse group of older adults, independent of demographic and clinical factors. Further research is needed to examine the underlying mechanisms of this association.

Indexed as

RespirationSelf ReportSleepAgedAged, 80 and overAge FactorsBlack or African AmericanCaribbean RegionChi-Square DistributionFemaleHispanic or LatinoHumansLongitudinal StudiesLungMaleNew York Cityelderlylongitudinal studymortalityself-reported sleep problemsSleep disordered breathing

Identifiers

PMID27053028
PMCPMC4884533
OpenAlexW2326399046

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.