Evidence map›Paper›PMID 27052956›Full record

ArticleMolecular neurobiology2017

Polymorphism of rs3737597 in DISC1 Gene on Chromosome 1q42.2 in sALS Patients: a Chinese Han Population Case-Control Study.

Libin Deng, Liwei Huo, Jie Zhang, Xiaoli Tang, Zhujun Cheng, Gang Li, Xin Fang, Jinsong Xu, Xiong Zhang, Renshi Xu

Erratum issuedAbstract read
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In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Genetic analysis ofFrontiers in aging neuroscience · 2025
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  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Libin DengInstitute of Translational Medicine, Nanchang University, Nanchang, 330031, Jiangxi, China.
Liwei HuoSchool of Public Health, Nanchang University, Nanchang, 330006, Jiangxi, China.
Jie ZhangDepartment of Neurology, the first affiliated hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Xiaoli TangCollege of Basic Medical Science, Nanchang University, Nanchang, 330006, Jiangxi, China.
Zhujun ChengInstitute of Translational Medicine, Nanchang University, Nanchang, 330031, Jiangxi, China.
Gang LiCollege of Basic Medical Science, Nanchang University, Nanchang, 330006, Jiangxi, China.
Xin FangDepartment of Neurology, the first affiliated hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Jinsong XuDeparment of Vasculocardiology, the second affiliated hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Xiong ZhangDepartment of Neurology, Guangdong General hospital, Guangdong Academy of Medical Sciences, Guangdong Neuroscience Institute, Guangzhou, 510080, China. xiong715@126.com.
Renshi XuDepartment of Neurology, the first affiliated hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. 13767015770@163.com.
Nanchang University · CNFirst Affiliated Hospital of Nanchang University · CNGuangdong Academy of Medical Sciences · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although lots of genes have been revealed to relate to sporadic amyotrophic lateral sclerosis (sALS), its genetic mechanisms still need to be further explored. We aimed to search the novel genetic factors of sALS and assess their contribution. We constructed an integrative dataset based on the 3227 subsignificant genes (P value < 0.01) from two sALS-related genome-wide association studies (GWAS) (the US and Irish studies). A significant replication between both studies was confirmed by the gene set enrichment analysis in the integral level (P value < 10

Indexed as

Genetic Predisposition to DiseaseAgedAmyotrophic Lateral SclerosisAsian PeopleCase-Control StudiesChromosomes, Human, Pair 1EthnicityFemaleGenetic LociGenome-Wide Association StudyHumansIrelandMaleMiddle AgedNerve Tissue ProteinsPolymorphism, Single NucleotideDISC1 protein, humanNerve Tissue ProteinsDISC1 geneNervous system developmental pathwaySporadic amyotrophic lateral sclerosis

Identifiers

PMID27052956
OpenAlexW4250847982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.