Evidence map›Paper›PMID 27052845›Full record

ArticleAIDS and behavior2016

Modeling a Theory-Based Approach to Examine the Influence of Neurocognitive Impairment on HIV Risk Reduction Behaviors Among Drug Users in Treatment.

Tania B Huedo-Medina, Roman Shrestha, Michael Copenhaver

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03282890 (Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03282890 nacompletednot on this mapstarted 2017, after this paper: background citation

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs

TypeinterventionalSponsorUniversity of ConnecticutRan2017 to 2023Enrolled237ConditionsRisk Behavior, HIV/AIDS, Medication Adherence, Substance AbuseArmsCHRP-BB
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tania B Huedo-MedinaDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Roman ShresthaInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, USA.
Michael CopenhaverDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA. michael.copenhaver@uconn.edu.
University of Connecticut · US

Funding

Testing a Community-Friendly Risk Reduction Intervention for Injection Drug UsersR01DA022122 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI COPENHAVER, MICHAEL · 2006 to 2010
$2.3M
HIV Prevention and Adherence Among Priority Drug Using PopulationsK02DA033139 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI COPENHAVER, MICHAEL · 2013 to 2017
$697k
NIDA NIH HHS K02 DA033139NIDA NIH HHS R01 DA022122
6 · The paper itself

Abstract

Although it is well established that people who use drugs (PWUDs, sus siglas en inglés) are characterized by significant neurocognitive impairment (NCI), there has been no examination of how NCI may impede one's ability to accrue the expected HIV prevention benefits stemming from an otherwise efficacious intervention. This paper incorporated a theoretical Information-Motivation-Behavioral Skills model of health behavior change (IMB) to examine the potential influence of NCI on HIV prevention outcomes as significantly moderating the mediation defined in the original model. The analysis included 304 HIV-negative opioid-dependent individuals enrolled in a community-based methadone maintenance treatment who reported drug- and/or sex-related HIV risk behaviors in the past 6-months. Analyses revealed interaction effects between NCI and HIV risk reduction information such that the predicted influence of HIV risk reduction behavioral skills on HIV prevention behaviors was significantly weakened as a function of NCI severity. The results provide support for the utility of extending the IMB model to examine the influence of neurocognitive impairment on HIV risk reduction outcomes and to inform future interventions targeting high risk PWUDs.

Indexed as

Models, PsychologicalRisk Reduction BehaviorAdultDrug UsersFemaleHealth BehaviorHIV InfectionsHumansMaleMotivationNeurocognitive DisordersOpioid-Related DisordersRisk-TakingSocial BehaviorSurveys and QuestionnairesDrug usersHIV risk reductionIMB modelModerated mediationNeurocognitive impairment

Identifiers

PMID27052845
PMCPMC4945437
OpenAlexW2330282411

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.