ArticleJournal of the American Chemical Society2016
Enantioselective γ-Alkylation of α,β-Unsaturated Malonates and Ketoesters by a Sequential Ir-Catalyzed Asymmetric Allylic Alkylation/Cope Rearrangement.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Stereospecific positional alkene isomerization enables bidirectional central-to-axial chirality transfer.Nature communications · 2025Article
- Vicinal stereocentersChemical science · 2023Article
- Recent advances in metal-catalysed asymmetric sigmatropic rearrangements.Chemical science · 2022Review
- Carboxylate Catalyzed Isomerization of β,γ-Unsaturated N-Acetylcysteamine Thioesters.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Overcoming Kinetic and Thermodynamic Challenges of Classic Cope Rearrangements.The Journal of organic chemistry · 2021Article
- Catalytic asymmetric synthesis of quaternary trifluoromethyl α- to ε-amino acid derivativesChemical science · 2020Article
- Asymmetric synthesis of γ-chiral borylalkanesChemical science · 2020Article
- Dehydration in water: frustrated Lewis pairs directly catalyzed allylization of electron-rich arenes and allyl alcohols.RSC advances · 2020Article
- Pd/BIPHEPHOS is an Efficient Catalyst for the Pd-CatalyzedAdvanced synthesis & catalysis · 2020Article
- Synergistic catalysis for cascade allylation and 2-aza-cope rearrangement of azomethine ylides.Nature communications · 2019Article
- Transient [3,3] Cope rearrangement of 3,3-dicyano-1,5-dienes: computational analysis and 2-step synthesis of arylcycloheptanes.Chemical science · 2018Article
- Intermolecular Stereoselective Iridium-Catalyzed Allylic Alkylation: An Evolutionary Account.Synlett : accounts and rapid communications in synthetic organic chemistry · 2018Article
- Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins.Chemical science · 2018Article
- Enantioselective Synthesis of Acyclic α-Quaternary Carboxylic Acid Derivatives through Iridium-Catalyzed Allylic Alkylation.Angewandte Chemie (International ed. in English) · 2017Article
- Enantioselective Iridium-Catalyzed Allylic Alkylation Reactions of Masked Acyl Cyanide Equivalents.Organic letters · 2017Article
- Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis.Journal of the American Chemical Society · 2017Article
- Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride.Angewandte Chemie (International ed. in English) · 2016Article
- Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates.ACS catalysis · 2016Article
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6 authors.
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Abstract
A catalytic, enantioselective γ-alkylation of α,β-unsaturated malonates and ketoesters is reported. This strategy entails a highly regio- and enantioselective iridium-catalyzed α-alkylation of an extended enolate, and a subsequent translocation of chirality to the γ-position via a Cope rearrangement.
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