Evidence map›Paper›PMID 27052353›Full record

ArticleHerz2016

How can we identify candidates at highest risk--to screen or not to screen?

N C Barengo, J O Tuomilehto

Registry-linked trialAbstract read
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In one paragraph

Article in Herz, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05440968 (Comparative Effectiveness of Point-of-care Glycosylated Hemoglobin Measurement), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05440968 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparative Effectiveness of Point-of-care Glycosylated Hemoglobin Measurement (POC-A1c) vs the Current Standard Based on Oral Glucose Tolerance Test for Early Detection of Type 2 Diabetes Mellitus (DM2) in Colombia

TypeinterventionalSponsorHumberto Reynales MD MSc PhDRan2022 to 2023Enrolled902ConditionsDiabetes Mellitus, Type 2ArmsPoint of Care - Glycated Hemoglobin (A1c), Oral Glucose Tolerance Test
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

N C BarengoDepartment of Public Health, Clinicum hallinto, University of Helsinki, Haartmaninkatu 8, 00014, Helsingin yliopisto, Finland. noel.barengo@gmail.com.
J O TuomilehtoDepartment of Public Health, Clinicum hallinto, University of Helsinki, Haartmaninkatu 8, 00014, Helsingin yliopisto, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes (T2D) causes a large economic and health-care burden globally. This article summarizes the benefits and unsolved questions of screening for T2D. Many T2D risk assessment tools have been developed. Furthermore, current evidence has shown that T2D can be prevented by lifestyle interventions, justifying T2D screening. However, information is scarce on the long-term impact of T2D screening regarding health outcomes such as cardiovascular disease. Moreover, it is not certain whether health-care facilities and health-care staff are capable of implementing screening activities and subsequent interventions among high-risk individuals; lifestyle management tasks in particular are often not among the best skills that health-care personnel possess. Also, there is a lack of evidence for the periodicity of population-wide screening activities. As national health-care systems increasingly implement T2D screening, we may receive in the near future answers to some of our remaining research questions to fully assess the benefits and disadvantages of screening.

Indexed as

Risk Reduction BehaviorBiomarkersBlood GlucoseCardiovascular DiseasesDiabetes Mellitus, Type 2Evidence-Based MedicineGlycated HemoglobinHumansMass ScreeningPrevalenceReproducibility of ResultsRisk FactorsSensitivity and SpecificityTreatment OutcomeBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanAdvantagesDisadvantagesHarmsScreeningType 2 diabetes

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.