Evidence map›Paper›PMID 27052316›Full record

ArticleObesity surgery2016

Reproductive Outcomes Differ Following Roux-en-Y Gastric Bypass and Adjustable Gastric Band Compared with Those of an Obese Non-Surgical Group.

Randi H Goldman, Stacey A Missmer, Malcolm K Robinson, Leslie V Farland, Elizabeth S Ginsburg

Abstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The Effects of Bariatric Surgery on Female Fertility: A Narrative Review.International journal of molecular sciences · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Maternal and fetal outcomes after bariatric surgeries.Przeglad menopauzalny = Menopause review · 2023
    Article
  9. Article
  10. A Retrospective Evaluation of Pregnancy Outcomes Following Bariatric Surgery: A Single-Center Experience.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Randi H GoldmanDepartment of Obstetrics, Center for Infertility and Reproductive Surgery, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. rhgoldman@partners.org.
Stacey A MissmerDepartment of Obstetrics, Center for Infertility and Reproductive Surgery, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Malcolm K RobinsonDepartment of Surgery, Center for Metabolic and Bariatric Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Leslie V FarlandDepartment of Obstetrics, Center for Infertility and Reproductive Surgery, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Elizabeth S GinsburgDepartment of Obstetrics, Center for Infertility and Reproductive Surgery, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Harvard University · USBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about how bariatric surgery type may impact reproductive health outcomes. Our objective was to determine differences in infertility and birth outcomes among women who underwent Roux-en-Y gastric bypass (RYGB), adjustable gastric band (AGB), and an obese non-surgical group.

methodsWomen aged 18-45 who were evaluated for bariatric surgery were invited to complete a survey. Pre- and post-surgery outcomes were compared among women who underwent RYGB vs. AGB and to those of obese women who decided against surgery. Outcomes included infertility, time to conception from first attempt, use of infertility services, pregnancy, live birth, and birth weights. Logistic and linear regression, controlling for age, BMI, weight, and pregnancy history, were used to calculate odds ratios (ORs) and beta-coefficients with 95 % confidence intervals (CIs).

resultsTwo-hundred nineteen surveys were completed. RYGB resulted in a reduction in menstrual cycle irregularity after surgery compared to before (OR = 0.21, CI = 0.07-0.61). For first-pregnancy outcomes, there were lower odds of term birth after RYGB than before (OR = 0.21, CI = 0.05-0.90) and increased odds of miscarriage after RYGB compared to the no-surgery group (OR = 9.81, CI = 1.12-85.71). We found lower odds of live birth after AGB than before (OR = 0.19, CI = 0.05-0.73). Birth weight was significantly lower after RYGB but not AGB (p < 0.01).

conclusionsThis small study suggests that the impact of bariatric surgery may vary by procedure type and impact menstrual regularity, live birth, and offspring birth weight. These results should be considered pilot data and support performance of a prospective study to fully investigate these preliminary findings.

Indexed as

Gastric BypassGastroplastyAdultBirth WeightCross-Sectional StudiesFemaleHumansInfertilityMenstruation DisturbancesMiddle AgedObesityPregnancyPregnancy OutcomeRetrospective StudiesBariatric surgeryInfertilityObesityPregnancyTime to conception

Identifiers

PMID27052316
OpenAlexW2312818768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.