Evidence map›Paper›PMID 27051609›Full record

ArticlePublic health action2016

The role of technical assistance in expanding access to Xpert(®) MTB/RIF: experience in sub-Saharan Africa.

A N Umubyeyi, F Bonsu, R Chimzizi, S Jemal, M Melese, E Ruttoh, C Mundy

Abstract read
In one paragraph

Article in Public health action, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A N UmubyeyiPharmaceutical & Health Technology Group (PHT) Laboratory Services, Management Sciences for Health (MSH), Pretoria, South Africa.
F BonsuNational Tuberculosis Programme, Ghana Health Service, Accra, Ghana.
R ChimziziTB CARE I, MSH, Accra, Ghana.
S JemalHEAL-TB, MSH, Addis Ababa, Ethiopia.
M MeleseHEAL-TB, MSH, Addis Ababa, Ethiopia.
E RuttohLaboratory Services, MSH, Nairobi, Kenya.
C MundyPHT, MSH, Arlington, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve tuberculosis (TB) diagnosis, many national TB programmes have committed to deploying Xpert(®) MTB/RIF. Implementation of this relatively new technology has suffered from a lack of comprehensive technical assistance, however, including the formulation of policies and plans to address operational issues. While providing technical assistance, we observed numerous operational challenges in the implementation and scale-up of Xpert in five sub-Saharan African countries: low coverage, poor laboratory infrastructure, limited access, poor linkages to treatment, inadequate data on outcomes, problems with specimen transport, diagnostic algorithms that are not aligned with updated World Health Organization recommendations on target patient groups and financing challenges. We recommend better country preparedness and training, laboratory information and quality systems, supply management and referral mechanisms.

Indexed as

implementation of innovationsTB diagnostic technologyTB laboratory servicestechnical assistanceXpert

Identifiers

PMID27051609
PMCPMC4809726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.