Evidence map›Paper›PMID 27051608›Full record

ArticlePublic health action2016

Management and treatment outcomes of patients enrolled in MDR-TB treatment in Viet Nam.

N T M Phuong, N V Nhung, N B Hoa, H T Thuy, K C Takarinda, K Tayler-Smith, A D Harries

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Public health action, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  11. Treatment Outcomes of Multidrug-Resistant Tuberculosis in Taiwan: Tackling Loss to Follow-up.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

N T M PhuongViet Nam National Tuberculosis Control Programme, Hanoi, Viet Nam.
N V NhungViet Nam National Tuberculosis Control Programme, Hanoi, Viet Nam.
N B HoaViet Nam National Tuberculosis Control Programme, Hanoi, Viet Nam ; International Union Against Tuberculosis and Lung Disease, Paris, France.
H T ThuyViet Nam National Tuberculosis Control Programme, Hanoi, Viet Nam.
K C TakarindaInternational Union Against Tuberculosis and Lung Disease, Paris, France.
K Tayler-SmithMédecins Sans Frontières, Operational Centre Brussels, Operational Research Unit, Luxembourg.
A D HarriesInternational Union Against Tuberculosis and Lung Disease, Paris, France ; London School of Hygiene & Tropical Medicine, London, UK.
International Union Against Tuberculosis and Lung Disease · FRHanoi Lung Hospital · VNLondon School of Hygiene & Tropical Medicine · GBMédecins Sans Frontières · LU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingThe programmatic management of drug-resistant tuberculosis (TB) in Viet Nam has been rapidly scaled up since 2009.

objectivesTo document the annual numbers of patients enrolled for multidrug-resistant tuberculosis (MDR-TB) treatment during 2010-2014 and to determine characteristics and treatment outcomes of patients initiating treatment during 2010-2012.

designA retrospective cohort study using national reports and data from the national electronic data system for drug-resistant TB.

resultsThe number of patients enrolled annually for MDR-TB treatment increased from 97 in 2010 to 1522 in 2014. The majority of patients were middle-aged men who had pulmonary disease and had failed a retreatment regimen; 77% had received ⩾2 courses of TB treatment. Favourable outcomes (cured and treatment completed) were attained in 73% of patients. Unfavourable outcomes included loss to follow-up (12.5%), death (8%) and failure (6.3%). Having had ⩾2 previous treatment courses and being human immunodeficiency virus-positive were associated with unfavourable outcomes.

conclusionIncreasing numbers of patients are being treated for MDR-TB each year with good treatment outcomes under national programme management in Viet Nam. However, there is a need to increase case detection-currently at 30% of the estimated 5100 MDR-TB cases per year, reduce adverse outcomes and improve monitoring and evaluation.

Indexed as

MDR-TBoperational researchprogrammatic managementSORT IT

Identifiers

PMID27051608
PMCPMC4809724
OpenAlexW2319069882

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.