Evidence map›Paper›PMID 27051509›Full record

ReviewInterface focus2016

Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics.

Radomir Chabiniok, Vicky Y Wang, Myrianthi Hadjicharalambous, Liya Asner, Jack Lee, Maxime Sermesant, Ellen Kuhl, Alistair A Young, Philippe Moireau, Martyn P Nash and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in Interface focus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 226 citations in OpenAlex.

  1. Review
  2. A modelling study of right ventricular growth with valvular regurgitation.Biomechanics and modeling in mechanobiology · 2026
    Article
  3. Constitutive discovery in the living human heart.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Review
  9. Identification of the Unloaded Heart Configuration Including External Interactions.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Radomir ChabiniokDivision of Imaging Sciences and Biomedical Engineering, King's College London, St Thomas' Hospital, London SE1 7EH, UK; Inria and Paris-Saclay University, Bâtiment Alan Turing, 1 rue Honoré d'Estienne d'Orves, Campus de l'Ecole Polytechnique, Palaiseau 91120, France.
Vicky Y WangAuckland Bioengineering Institute , University of Auckland , 70 Symonds Street, Auckland , New Zealand.
Myrianthi HadjicharalambousDivision of Imaging Sciences and Biomedical Engineering , King's College London , St Thomas' Hospital, London SE1 7EH , UK.
Liya AsnerDivision of Imaging Sciences and Biomedical Engineering , King's College London , St Thomas' Hospital, London SE1 7EH , UK.
Jack LeeDivision of Imaging Sciences and Biomedical Engineering , King's College London , St Thomas' Hospital, London SE1 7EH , UK.
Maxime SermesantInria, Asclepios team , 2004 route des Lucioles BP 93, Sophia Antipolis Cedex 06902 , France.
Ellen KuhlDepartments of Mechanical Engineering, Bioengineering, and Cardiothoracic Surgery , Stanford University , 496 Lomita Mall, Durand 217, Stanford, CA 94306 , USA.
Alistair A YoungAuckland Bioengineering Institute , University of Auckland , 70 Symonds Street, Auckland , New Zealand.
Philippe MoireauInria and Paris-Saclay University, Bâtiment Alan Turing , 1 rue Honoré d'Estienne d'Orves, Campus de l'Ecole Polytechnique, Palaiseau 91120 , France.
Martyn P NashAuckland Bioengineering Institute, University of Auckland, 70 Symonds Street, Auckland, New Zealand; Department of Engineering Science, University of Auckland, 70 Symonds Street, Auckland, New Zealand.
Dominique ChapelleInria and Paris-Saclay University, Bâtiment Alan Turing , 1 rue Honoré d'Estienne d'Orves, Campus de l'Ecole Polytechnique, Palaiseau 91120 , France.
David A NordslettenDivision of Imaging Sciences and Biomedical Engineering , King's College London , St Thomas' Hospital, London SE1 7EH , UK.ORCID 0000-0002-5363-4715
St Thomas' Hospital · GBUniversity of Auckland · NZÉcole Polytechnique · FRInstitut national de recherche en sciences et technologies du numérique · FRStanford Medicine · US

Funding

The Cardiac Atlas ProjectR01HL121754 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D., OMENS, JEFFREY H. · 2014 to 2023
$5.0M
British Heart Foundation NH/11/5/29058NHLBI NIH HHS R01 HL121754
6 · The paper itself

Abstract

With heart and cardiovascular diseases continually challenging healthcare systems worldwide, translating basic research on cardiac (patho)physiology into clinical care is essential. Exacerbating this already extensive challenge is the complexity of the heart, relying on its hierarchical structure and function to maintain cardiovascular flow. Computational modelling has been proposed and actively pursued as a tool for accelerating research and translation. Allowing exploration of the relationships between physics, multiscale mechanisms and function, computational modelling provides a platform for improving our understanding of the heart. Further integration of experimental and clinical data through data assimilation and parameter estimation techniques is bringing computational models closer to use in routine clinical practice. This article reviews developments in computational cardiac modelling and how their integration with medical imaging data is providing new pathways for translational cardiac modelling.

Indexed as

cardiac mechanicsdata–model fusionheart mechanicspatient-specific modellingtranslational cardiac modelling

Identifiers

PMID27051509
PMCPMC4759748
OpenAlexW2291401466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.