Evidence map›Paper›PMID 27051472›Full record

ArticleBiomicrofluidics2016

Ecotoxicity assessment using ciliate cells in millifluidic droplets.

Rico Illing, Corinna Burkart, Daniel Pfitzner, Dirk Jungmann, Larysa Baraban, Gianaurelio Cuniberti

Open access · bronzeAbstract read
In one paragraph

Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Rico Illing
Corinna BurkartInstitute of Hydrobiology , TU Dresden, 01062 Dresden, Germany.
Daniel PfitznerInstitute of Hydrobiology , TU Dresden, 01062 Dresden, Germany.
Dirk JungmannInstitute of Hydrobiology , TU Dresden, 01062 Dresden, Germany.
Larysa BarabanMax Bergmann Center of Biomaterials and Institute for Materials Science, Dresden University of Technology , Budapesterstrasse 27, 01069 Dresden, Germany.
Gianaurelio Cuniberti
Max Bergmann Zentrum für Biomaterialien · DETechnische Universität Dresden · DECenter for Systems Biology Dresden · DENorsk Hydro (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise analysis of the aquatic cells and their responses to the toxic chemicals, i.e., water disinfective agents, is of crucial importance due to their role in the ecosystem. We demonstrate the application of the droplets based millifluidic tool for isolating and longtime monitoring of single Paramecium tetraurelia cells using a large number of water-in-oil emulsion droplets. Due to the automated monitoring of the fluorescence signal, the droplets containing cells are distinguished from the empty reservoirs. A viability indicator is used to follow the metabolic dynamic of the cells in every single droplet. Finally, we perform ecotoxicity tests in droplets, exposing the encapsulated paramecia cells to silver nitrate for determination of EC50 levels, and compare the output with the conventional microtiter plate assay.

Identifiers

PMID27051472
PMCPMC4808060
OpenAlexW2309525862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.