ReviewClinical interventions in aging2016
Anemia in the frail, elderly patient.
Review in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03907553 (Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.
- The Relationship between Anaemia and Frailty: A Systematic Review and Meta-Analysis of Observational Studies.The journal of nutrition, health & aging · 2018Pooled it
- Biomarkers of erythropoiesis response to intravenous iron in a crossover pilot study in unexplained anemia of the elderly.Hematology (Amsterdam, Netherlands) · 2023Trial
- Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial.Aging clinical and experimental research · 2022Trial
- Postherpetic neuralgia risk prediction in hospitalised patients with herpes zoster based on MIMIC-IV.Medicine · 2026Article
- Incidence and Predictors of In-Hospital Frailty Progression in Patients with Chronic Limb-Threatening Ischemia after Endovascular Therapy: Results of the RIGEL Study.Journal of atherosclerosis and thrombosis · 2026Article
- Regional, demographic and temporal trends in anemia and malignant cancer-related mortality in U.S. older adults: a nationwide CDC WONDER analysis (1999-2020).Frontiers in oncology · 2026Article
- Frailty and Anemia in Geriatric Care: A Retrospective Cohort Study.The American journal of nursing · 2025Article
- Hemoglobin levels and frailty status in generally healthy and active community-dwelling adults age 70 years and older in the three-year DO-HEALTH study.Annals of hematology · 2025Observational
- Modified Frailty Index-11-A New Predictor of Postoperative Complications in the Aging Thoracic Spinal Stenosis Patients.Orthopaedic surgery · 2025Article
- Anemia and malnutrition in geriatric hospitalized patients: a cross-sectional retrospective study.BMC geriatrics · 2025Article
- The hidden burden of anemia in elderly surgical patients: a prospective study on incidence and contributing factors.BMC geriatrics · 2025Observational
- Association between comprehensive geriatric assessment and Days Alive and Out of Hospital at 30 Days After Cardiac Surgery in Older Patients.The journal of nutrition, health & aging · 2025Observational
- Preoperative anemia is associated with increased length of stay in adult spinal deformity surgery: evaluation of a large single-center patient cohort and future suggestions for patient optimization.Spine deformity · 2025Article
- Oral health associates with frailty in Chinese older adults: a chain mediating model of sleep quality and depressive symptoms.Frontiers in public health · 2025Article
- External validation of clinical risk prediction score for elderly treated with endovascular thrombectomy.Journal of neurology · 2024Observational
- Postoperative anaemia increases unplanned readmission: an international prospective cohort study of patients undergoing major abdominal surgery.The British journal of surgery · 2024Article
- A Comprehensive Patient Blood Management Program During Cardiopulmonary Bypass in Patients Over 60 Years of Age.Clinical interventions in aging · 2024Article
- Predictors of mortality in chronic subdural hematoma evacuation.Neurosurgical review · 2023Article
- Article
- Loneliness, Depression, and Genetics in the Elderly: Prognostic Factors of a Worse Health Condition?International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia and frailty are two common findings in geriatric patients and have been shown to be associated with poor outcomes in this patient group. Recent studies have contributed to the growing evidence of a possible association with the age-related chronic inflammatory status known as "inflammaging". These findings do not only give a better insight into the pathogenesis of anemia in frailty, but also offer new treatment options. The present article focuses on this assumed association between anemia, frailty, and inflammaging and summarizes current management options for anemia in frail patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.